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Timothy J Shepodd

Explore the profile of Timothy J Shepodd including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 62
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Recent Articles
1.
Reichmuth D, Shepodd T, Kirby B
Anal Chem . 2005 Apr; 77(9):2997-3000. PMID: 15859622
Rapid microchip reversed-phase HPLC of peptides and proteins at pressure gradients of 12 bar/cm (180 psi/cm) has been performed using a microdevice that integrates subnanoliter on-chip injection and separation with...
2.
Kirby B, Reichmuth D, Renzi R, Shepodd T, Wiedenman B
Lab Chip . 2005 Jan; 5(2):184-90. PMID: 15672133
This paper presents the first systematic engineering study of the impact of chemical formulation and surface functionalization on the performace of free-standing microfluidic polymer elements used for high-pressure fluid control...
3.
Reichmuth D, Shepodd T, Kirby B
Anal Chem . 2004 Sep; 76(17):5063-8. PMID: 15373443
A high-pressure (> 3 MPa) on-chip injector has been developed for microchip applications including HPLC. The mechanical injector is implemented using in situ photopolymerization of fluorinated acrylates inside wet-etched silica...
4.
Kirby B, Wheeler A, Zare R, Fruetel J, Shepodd T
Lab Chip . 2004 Apr; 3(1):5-10. PMID: 15100798
Spatial patterning of thin polyacrylamide films bonded to self-assembled monolayers on silica microchannels is described as a means for manipulating cell-adhesion and electroosmotic properties in microchips. Streaming potential measurements indicate...
5.
Song S, Singh A, Shepodd T, Kirby B
Anal Chem . 2004 Apr; 76(8):2367-73. PMID: 15080749
Chip-level integration of microdialysis membranes is described using a novel method for in situ photopatterning of porous polymer features. Rapid and inexpensive fabrication of nanoporous microdialysis membranes in microchips is...
6.
Kirby B, Shepodd T, Hasselbrink Jr E
J Chromatogr A . 2002 Dec; 979(1-2):147-54. PMID: 12498243
We present a microchip-based, voltage-addressable on/off valve architecture that is fundamentally consistent with the pressures and solvents employed for high-pressure liquid chromatography. Laser photopatterning of polymer monoliths inside glass microchannels...
7.
Hasselbrink Jr E, Shepodd T, Rehm J
Anal Chem . 2002 Oct; 74(19):4913-8. PMID: 12380812
We have developed a nonstick polymer formulation for creating moving parts inside of microfluidic channels and have applied the technique to create piston-based devices that overcome several microfluidic flow control...
8.
Throckmorton D, Shepodd T, Singh A
Anal Chem . 2002 Feb; 74(4):784-9. PMID: 11866058
A microfabricated glass chip containing fluidic channels filled with polymer monolith has been developed for reversed-phase electrochromatography. Acrylate-based porous polymer monoliths were cast in the channels by photopolymerization to serve...