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Aaron R Wheeler

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Articles 141
Citations 2451
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Recent Articles
1.
Salari A, Camacho Valenzuela J, Le N, Dahmer J, Sklavounos A, Kan C, et al.
Lab Chip . 2025 Feb; PMID: 39991902
We report methods that improve the manipulation of magnetic beads using digital microfluidics (DMF) that can enhance the performance of single molecule array (Simoa) digital protein assays in miniaturized analytical...
2.
Li G, Xu B, Wang X, Yu J, Zhang Y, Fu R, et al.
Adv Mater . 2025 Feb; :e2417742. PMID: 39945115
Micromachines capable of performing diverse mechanical tasks in complex and constrained microenvironments are of great interest. Despite important milestones in this pursuit, until now, micromachines are confined to actuation within...
3.
Bandura J, Chan C, Sun H, Wheeler A, Feng Z
J Proteome Res . 2024 Dec; 24(1):27-45. PMID: 39658033
Long-term memory (LTM) formation relies on protein synthesis; however, the full complement of proteins crucial to LTM formation remains unknown in any system. Using an aversive operant conditioning model of...
4.
Lant J, Frasheri J, Kwon T, Tsang C, Li B, Decombe S, et al.
Lab Chip . 2024 Nov; 24(24):5398-5412. PMID: 39565292
In recent years, monoclonal antibodies (mAbs) have become a powerful tool in the treatment of human diseases. Currently, over 100 mAbs have received approval for therapeutic use in the US,...
5.
Elsayed M, Bodo L, Gaoiran C, Keuhnelian P, Dosajh A, Luk V, et al.
Adv Sci (Weinh) . 2024 Sep; 11(41):e2405712. PMID: 39230280
Forensic case samples collected in sexual assaults typically contain DNA from multiple sources, which complicates short-tandem repeat (STR) profiling. These samples are typically sent to a laboratory to separate the...
6.
Casasbuenas D, Kortebi I, Gora C, Scott E, Gomes C, Oliveira Jr M, et al.
Glia . 2024 Jun; 72(9):1693-1706. PMID: 38852127
Astrocytes that reside in superficial (SL) and deep cortical layers have distinct molecular profiles and morphologies, which may underlie specific functions. Here, we demonstrate that the production of SL and...
7.
Scott E, Safarian N, Casasbuenas D, Dryden M, Tockovska T, Ali S, et al.
Nat Commun . 2024 Feb; 15(1):1584. PMID: 38383565
Astrocytes, a type of glial cell in the central nervous system (CNS), adopt diverse states in response to injury that are influenced by their location relative to the insult. Here,...
8.
Nemr C, Sklavounos A, Wheeler A, Kelley S
SLAS Discov . 2023 Dec; :100133. PMID: 38101571
The Publisher regrets that this article is an accidental duplication of an article previously published at http://dx.doi.org/10.1016/j.slast.2022.10.001. This duplication was due to an error in the publishing workflow and was...
9.
Ho M, Sathishkumar N, Sklavounos A, Sun J, Yang I, Nichols K, et al.
Lab Chip . 2023 Nov; 24(1):63-73. PMID: 37987330
There is great enthusiasm for using loop-mediated isothermal amplification (LAMP) in point-of-care nucleic acid amplification tests (POC NAATs), as an alternative to PCR. While isothermal amplification techniques like LAMP eliminate...
10.
Bolotin S, Osman S, Halperin S, Severini A, Ward B, Sadarangani M, et al.
Vaccine . 2023 Oct; 41(46):6775-6781. PMID: 37827968
On November 18-19, 2019, the Immunity of Canadians and Risk of Epidemics (iCARE) Network convened a workshop in Toronto, Ontario, Canada. The objectives of the workshop were to raise the...