Timothy E Corcoran
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Explore the profile of Timothy E Corcoran including associated specialties, affiliations and a list of published articles.
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56
Citations
731
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Recent Articles
11.
Donaldson S, Laube B, Mogayzel P, Corcoran T, Pilewski J, Ceppe A, et al.
J Cyst Fibros
. 2021 Jun;
21(1):143-145.
PMID: 34083123
CFTR function is required for normal mucociliary clearance (MCC) and cough-assisted clearance (CC). Lumacaftor-ivacaftor is approved for use in people with cystic fibrosis (CF) carrying two copies of F508del-CFTR. In...
12.
Corcoran T, Huber A, Hill S, Locke L, Weber L, Muthukrishnan A, et al.
Chest
. 2021 May;
160(5):1604-1613.
PMID: 34029561
Background: Although mucus plugging is a well-reported feature of asthma, whether asthma and type 2 inflammation affect mucociliary clearance (MCC) is unknown. Research Question: Does type 2 inflammation influence mucus...
13.
Corcoran T
Ann Transl Med
. 2021 May;
9(7):595.
PMID: 33987293
Pediatric patients are very dependent on inhaled aerosol medications. There are significant differences in how these aerosols deposit in the lungs of children adults that may affect the efficacy of...
14.
Adams P, Corcoran T, Lin J, Weiner D, Sanchez-de-Toledo J, Lo C
Front Cardiovasc Med
. 2021 May;
8:652158.
PMID: 33969015
Infants undergoing congenital cardiac surgery with cardiopulmonary bypass are at high risk for respiratory complications. As impaired airway mucociliary clearance (MCC) can potentially contribute to pulmonary morbidity, our study objective...
15.
Boorgu D, Dharmarajan H, Sim E, Goyal L, Freiser M, Weinstock M, et al.
Ann Otol Rhinol Laryngol
. 2021 Mar;
130(11):1245-1253.
PMID: 33730891
Objectives: Define aerosol and droplet risks associated with routine otolaryngology clinic procedures during the COVID-19 era. Methods: Clinical procedures were simulated in cadaveric heads whose oral and nasal cavities were...
16.
Freiser M, Dharmarajan H, Boorgu D, Sim E, Corcoran T, Jabbour N, et al.
Otol Neurotol
. 2021 Mar;
42(4):614-622.
PMID: 33710998
Hypothesis: Aerosols are generated during mastoidectomy and mitigation strategies may effectively reduce aerosol spread. Background: An objective understanding of aerosol generation and the effectiveness of mitigation strategies can inform interventions...
17.
Sim E, Dharmarajan H, Boorgu D, Goyal L, Weinstock M, Whelan R, et al.
Ann Otol Rhinol Laryngol
. 2020 Aug;
130(3):280-285.
PMID: 32795090
Objective: During the COVID-19 era, a reliable method for tracing aerosols and droplets generated during otolaryngology procedures is needed to accurately assess contamination risk and to develop mitigation measures. Prior...
18.
Fink J, Ehrmann S, Li J, Dailey P, McKiernan P, Darquenne C, et al.
J Aerosol Med Pulm Drug Deliv
. 2020 Aug;
33(6):300-304.
PMID: 32783675
National and international guidelines recommend droplet/airborne transmission and contact precautions for those caring for coronavirus disease 2019 (COVID-19) patients in ambulatory and acute care settings. The severe acute respiratory syndrome...
19.
Dharmarajan H, Freiser M, Sim E, Boorgu D, Corcoran T, Wang E, et al.
Otolaryngol Head Neck Surg
. 2020 Aug;
164(2):285-293.
PMID: 32779964
Objective: To define the aerosol and droplet risks associated with endonasal drilling and to identify mitigation strategies. Study Design: Simulation series with fluorescent 3-dimensional (3D) printed sinonasal models and deidentified...
20.
Serrano Castillo F, Bertrand C, Myerburg M, Shapiro M, Corcoran T, Parker R
J Pharmacokinet Pharmacodyn
. 2019 Sep;
46(5):457-472.
PMID: 31494805
Cystic fibrosis (CF) disease is caused by mutations affecting the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel expressed in the mucosal side of epithelial...