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Tim Vanmierlo

Explore the profile of Tim Vanmierlo including associated specialties, affiliations and a list of published articles. Areas
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Articles 105
Citations 1471
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Recent Articles
1.
Schepers M, Vangansewinkel T, Libberecht K, Jeurissen H, Jacobs D, Piccart E, et al.
Biomed Pharmacother . 2025 Jan; 183:117828. PMID: 39823724
Charcot-Marie-Tooth disease type 1A (CMT1A) is an inherited peripheral neuropathy caused by a duplication of the peripheral myelin protein 22 (PMP22) gene. It is primarily marked by Schwann cell dedifferentiation...
2.
Schuetz L, Duran G, Baeten P, Lintsen D, Hermans D, Chenine S, et al.
Biol Sex Differ . 2024 Dec; 15(1):105. PMID: 39696610
Obesity is a growing pandemic that increases the risk for cardiovascular diseases, type 2 diabetes, and particularly in women also the risk of cancer and neurodegenerative disorders such as dementia...
3.
Vanbrabant K, Rasking L, Vangeneugden M, Bove H, Ameloot M, Vanmierlo T, et al.
Part Fibre Toxicol . 2024 Dec; 21(1):51. PMID: 39633442
The effects of ultrafine particle (UFP) inhalation on neurodevelopment, especially during critical windows of early life, remain largely unexplored. The specific time windows during which exposure to UFP might be...
4.
Van Broeckhoven J, Mussen F, Schepers M, Vanmierlo T, Hellings N
FEBS J . 2024 Nov; 292(1):47-51. PMID: 39548653
Oligodendrocytes (OLGs) are the myelin-producing cells in the central nervous system (CNS). Following injury, these cells are prone to death, leading to demyelination and, eventually, axonal loss and neurodegeneration. Upon...
5.
Veggel L, Voets A, Vanmierlo T, Schreiber R
Neural Regen Res . 2024 Aug; 20(6):1717-1718. PMID: 39104109
No abstract available.
6.
Leenders F, Koole L, Slaets H, Tiane A, van den Hove D, Vanmierlo T
Mech Ageing Dev . 2024 Jul; 220:111959. PMID: 38950628
Oligodendrocyte precursor cells (OPCs) comprise 5-8 % of the adult glial cell population and stand out as the most proliferative cell type in the central nervous system (CNS). OPCs are...
7.
Rombaut B, Schepers M, Tiane A, Mussen F, Koole L, Kessels S, et al.
Cells . 2024 Jun; 13(12. PMID: 38920631
Microglia activity can drive excessive synaptic loss during the prodromal phase of Alzheimer's disease (AD) and is associated with lowered cyclic adenosine monophosphate (cAMP) due to cAMP phosphodiesterase 4B (PDE4B)....
8.
Donders Z, Skorupska I, Willems E, Mussen F, Van Broeckhoven J, Carlier A, et al.
Biomed Pharmacother . 2024 Jun; 177:117009. PMID: 38908196
Cyclic adenosine monophosphate (cAMP) is a key second messenger that regulates signal transduction pathways pivotal for numerous biological functions. Intracellular cAMP levels are spatiotemporally regulated by their hydrolyzing enzymes called...
9.
Martens N, Zhan N, Yam S, Leijten F, Palumbo M, Caspers M, et al.
Nutrients . 2024 Jun; 16(11). PMID: 38892548
We previously demonstrated that diet supplementation with seaweed () prevented AD-related pathology in a mouse model of Alzheimer's Disease (AD). Here, we tested a lipid extract of seaweed () and...
10.
Schepers M, Hendrix S, Mussen F, Van Breedam E, Ponsaerts P, Lemmens S, et al.
Neurotherapeutics . 2024 May; 21(4):e00372. PMID: 38760316
Spinal cord injury (SCI) is a life-changing event that severely impacts the patient's quality of life. Modulating neuroinflammation, which exacerbates the primary injury, and stimulating neuro-regenerative repair mechanisms are key...