Jack van Horssen
Overview
Explore the profile of Jack van Horssen including associated specialties, affiliations and a list of published articles.
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Articles
110
Citations
5536
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Recent Articles
1.
Rodriguez-Mogeda C, van Lierop Z, van der Pol S, Coenen L, Hogenboom L, Kamermans A, et al.
J Neuroinflammation
. 2023 Sep;
20(1):215.
PMID: 37752582
Background: Recent studies suggest that extended interval dosing of ocrelizumab, an anti-B cell therapy, does not affect its clinical effectiveness in most patients with multiple sclerosis (MS). However, it remains...
2.
Carvalho A, Branco V, van Horssen J, Saso L
Front Cell Neurosci
. 2023 May;
17:1198669.
PMID: 37153636
No abstract available.
3.
Spaas J, Goulding R, Keytsman C, Fonteyn L, van Horssen J, Jaspers R, et al.
J Cachexia Sarcopenia Muscle
. 2022 Aug;
13(5):2537-2550.
PMID: 35929063
Background: Patients with multiple sclerosis (MS) experience reduced exercise tolerance that substantially reduces quality of life. The mechanisms underpinning exercise intolerance in MS are not fully clear. This study aimed...
4.
Rodriguez-Mogeda C, Rodriguez-Lorenzo S, Attia J, van Horssen J, Witte M, de Vries H
Biomolecules
. 2022 Jun;
12(6).
PMID: 35740925
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) known for the manifestation of demyelinated lesions throughout the CNS, leading to neurodegeneration. To date, not all...
5.
Spaas J, Franssen W, Keytsman C, Blancquaert L, Vanmierlo T, Bogie J, et al.
J Neuroinflammation
. 2021 Nov;
18(1):255.
PMID: 34740381
Background: Multiple sclerosis (MS) is a chronic autoimmune disease driven by sustained inflammation in the central nervous system. One of the pathological hallmarks of MS is extensive free radical production....
6.
van Olst L, Rodriguez-Mogeda C, Picon C, Kiljan S, James R, Kamermans A, et al.
Acta Neuropathol
. 2021 Mar;
141(6):881-899.
PMID: 33779783
Meningeal inflammation strongly associates with demyelination and neuronal loss in the underlying cortex of progressive MS patients, thereby contributing significantly to clinical disability. However, the pathological mechanisms of meningeal inflammation-induced...
7.
Spaas J, Veggel L, Schepers M, Tiane A, van Horssen J, Wilson 3rd D, et al.
Cell Mol Life Sci
. 2021 Mar;
78(10):4615-4637.
PMID: 33751149
Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that occurs due...
8.
Picon C, Jayaraman A, James R, Beck C, Gallego P, Witte M, et al.
Acta Neuropathol
. 2021 Feb;
141(4):585-604.
PMID: 33569629
Sustained exposure to pro-inflammatory cytokines in the leptomeninges is thought to play a major role in the pathogenetic mechanisms leading to cortical pathology in multiple sclerosis (MS). Although the molecular...
9.
Rosenkranz S, Shaposhnykov A, Trager S, Engler J, Witte M, Roth V, et al.
Elife
. 2021 Feb;
10.
PMID: 33565962
While transcripts of neuronal mitochondrial genes are strongly suppressed in central nervous system inflammation, it is unknown whether this results in mitochondrial dysfunction and whether an increase of mitochondrial function...
10.
Vanmierlo T, van Horssen J, Hellings N, Broux B
Front Immunol
. 2020 Aug;
11:1425.
PMID: 32793198
No abstract available.