Tim H M Huang
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Explore the profile of Tim H M Huang including associated specialties, affiliations and a list of published articles.
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28
Citations
672
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Recent Articles
1.
Chen Z, Ye Z, Soccio R, Nakadai T, Hankey W, Zhao Y, et al.
Nucleic Acids Res
. 2022 Apr;
50(8):4450-4463.
PMID: 35394046
Mediator activates RNA polymerase II (Pol II) function during transcription, but it remains unclear whether Mediator is able to travel with Pol II and regulate Pol II transcription beyond the...
2.
Adnan N, Zand M, Huang T, Ruan J
IEEE/ACM Trans Comput Biol Bioinform
. 2021 Oct;
19(3):1344-1353.
PMID: 34662279
Interpretability of machine learning (ML) models represents the extent to which a model's decision-making process can be understood by model developers and/or end users. Transcriptomics-based cancer prognosis models, for example,...
3.
Lieberman B, Kusi M, Hung C, Chou C, He N, Ho Y, et al.
J Transl Genet Genom
. 2021 Jul;
5:1-21.
PMID: 34322662
Among single-cell analysis technologies, single-cell RNA-seq (scRNA-seq) has been one of the front runners in technical inventions. Since its induction, scRNA-seq has been well received and undergone many fast-paced technical...
4.
Adnan N, Liu Z, Huang T, Ruan J
BMC Med Genomics
. 2020 Apr;
13(Suppl 5):40.
PMID: 32241278
Background: Discovering a highly accurate and robust gene signature for the prediction of breast cancer metastasis from gene expression profiling of primary tumors is one of the most challenging tasks...
5.
Shen-Gunther J, Wang Y, Lai Z, Poage G, Perez L, Huang T
BMC Genomics
. 2017 Mar;
18(1):231.
PMID: 28288568
Background: Human papillomavirus (HPV) is the carcinogen of almost all invasive cervical cancer and a major cause of oral and other anogenital malignancies. HPV genotyping by dideoxy (Sanger) sequencing is...
6.
Noonepalle S, Gu F, Lee E, Choi J, Han Q, Kim J, et al.
Cancer Immunol Res
. 2017 Mar;
5(4):330-344.
PMID: 28264810
Triple-negative breast cancer (TNBC) cells are modulated in reaction to tumor-infiltrating lymphocytes. However, their specific responses to this immune pressure are unknown. In order to address this question, we first...
7.
Jadhav R, Wang Y, Hsu Y, Liu J, Garcia D, Lai Z, et al.
J Vis Exp
. 2016 Nov;
(116).
PMID: 27842364
Methylation is one of the essential epigenetic modifications to the DNA, which is responsible for the precise regulation of genes required for stable development and differentiation of different tissue types....
8.
Tian Y, Wong V, Wong G, Yang W, Sun H, Shen J, et al.
Cancer Res
. 2015 Sep;
75(22):4803-16.
PMID: 26383163
The growing epidemic of obesity, which causes nonalcoholic fatty liver disease (NAFLD) and the more severe phenotype nonalcoholic steatohepatitis (NASH), has paralleled the increasing incidence of hepatocellular carcinoma (HCC). Accumulating...
9.
Ghosh S, Gu F, Wang C, Lin C, Liu J, Wang H, et al.
Breast Cancer Res Treat
. 2014 Sep;
147(3):653-9.
PMID: 25234841
Early pregnancy in women by the age of 20 is known to have a profound effect on reduction of lifelong breast cancer risk as compared to their nulliparous counterparts. Additional...
10.
Liu B, Yi J, Sv A, Lan X, Ma Y, Huang T, et al.
BMC Genomics
. 2014 Feb;
14 Suppl 8:S3.
PMID: 24564479
Background: Many computational programs have been developed to identify enriched regions for a single biological ChIP-seq sample. Given that many biological questions are often asked to compare the difference between...