Tim Erkens
Overview
Explore the profile of Tim Erkens including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
137
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0
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Recent Articles
1.
Khan S, Marquez-Martinez S, Erkens T, de Wilde A, Costes L, Vinken P, et al.
Vaccines (Basel)
. 2023 Dec;
11(12).
PMID: 38140195
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a very rare but serious adverse reaction that can occur after Ad26.COV2.S vaccination in humans, leading to thrombosis at unusual anatomic sites. One hypothesis...
2.
Erkens T, Bueters R, van Heerden M, Cuyckens F, Vreeken R, Goeminne N, et al.
J Appl Toxicol
. 2018 May;
38(10):1282-1292.
PMID: 29781175
The intestinal barrier controls intestinal permeability, and its disruption has been associated with multiple diseases. Therefore, preclinical safety biomarkers monitoring barrier integrity are essential during the development of drugs targeting...
3.
Erkens T, Goeminne N, Kegels A, Byloos M, Vinken P
J Pharmacol Toxicol Methods
. 2018 Jan;
91:43-49.
PMID: 29371052
Introduction: Multiplex immunoassays are an important tool in biomarker research during preclinical drug development. However, information regarding analytical performance of commercial multiplex assays for animal species is often limited. To...
4.
Erkens T, Van den Sande L, Witters J, Verbraeken F, Looszova A, Feyen B
Vet Clin Pathol
. 2017 Jun;
46(3):416-421.
PMID: 28582600
Background: A marked decrease in thrombocyte count was observed between subsequent measurements of the same EDTA blood sample in several minipigs, but little information was available explaining this finding. Objectives:...
5.
Borghys H, Van Broeck B, Dhuyvetter D, Jacobs T, De Waepenaert K, Erkens T, et al.
J Alzheimers Dis
. 2016 Dec;
56(2):763-774.
PMID: 28035921
Understanding differences in Alzheimer's disease biomarkers before the pathology becomes evident can contribute to an improved understanding of disease pathogenesis and treatment. A decrease in amyloid-β (Aβ)42 in cerebrospinal fluid...
6.
Darville N, van Heerden M, Erkens T, Jonghe S, Vynckier A, De Meulder M, et al.
Toxicol Pathol
. 2015 Dec;
44(2):189-210.
PMID: 26698322
Long-acting injectable (LAI) drug suspensions consist of drug nano-/microcrystals suspended in an aqueous vehicle and enable prolonged therapeutic drug exposure up to several months. The examination of injection site reactions...
7.
Bruynsteen L, Erkens T, Peelman L, Ducatelle R, Janssens G, Harris P, et al.
BMC Vet Res
. 2013 Dec;
9:240.
PMID: 24295090
Background: In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact...
8.
Expression and localization of angiogenic growth factors in developing porcine mesonephric glomeruli
De Spiegelaere W, Cornillie P, Erkens T, Van Loo D, Casteleyn C, Van Poucke M, et al.
J Histochem Cytochem
. 2010 Aug;
58(12):1045-56.
PMID: 20713984
The development and growth of renal glomeruli is regulated by specific angiogenic growth factors, including vascular endothelial growth factor (VEGF) and the angiopoietins (ANGPT1 and ANGPT2). The expression of these...
9.
Van Poucke M, Melkebeek V, Erkens T, Van Zeveren A, Cox E, Peelman L
BMC Genet
. 2009 Oct;
10:64.
PMID: 19807916
Background: Because prostaglandins are involved in many (patho)physiological processes, SLCO2A1 was already characterized in several species in an attempt to unravel specific processes/deficiencies. Here, we describe the molecular cloning and...
10.
Erkens T, Bilek K, Van Zeveren A, Peelman L
BMC Res Notes
. 2008 Dec;
1:138.
PMID: 19114011
Background: Peroxisome proliferator-activated receptor gamma coactivator 1alpha (PPARGC1A) is a coactivator with a vital and central role in fat and energy metabolism. It is considered to be a candidate gene...