Tilman Sauerbruch
Overview
Explore the profile of Tilman Sauerbruch including associated specialties, affiliations and a list of published articles.
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270
Citations
5003
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Recent Articles
61.
Gonzalez-Carmona M, Quasdorff M, Vogt A, Tamke A, Yildiz Y, Hoffmann P, et al.
Antiviral Res
. 2012 Nov;
97(1):49-59.
PMID: 23142319
Background: The 5'-noncoding region (5'NCR) of the HCV-genome comprises an internal ribosome entry site essential for HCV-translation/replication. Phosphorothioate oligodeoxynucleotides (tS-ODN) complementary to this region can inhibit HCV-translation in vitro. In...
62.
Kellner P, Anadol E, Huneburg R, Hundt F, Bos D, Klein B, et al.
Eur J Gastroenterol Hepatol
. 2012 Nov;
25(3):368-72.
PMID: 23114792
Background/aims: The noninvasive measurement of liver stiffness using transient elastography (TE) is increasingly being used alongside liver biopsy. However, several conditions may lead to higher liver stiffness values without reflecting...
63.
Trebicka J, Anadol E, Elfimova N, Strack I, Roggendorf M, Viazov S, et al.
J Hepatol
. 2012 Oct;
58(2):234-9.
PMID: 23085648
Background & Aims: The progression of liver fibrosis in patients with chronic hepatitis C (CHC) is important to decide on the treatment of the virus. As liver biopsy and liver...
64.
Garcia-Pagan J, Di Pascoli M, Caca K, Laleman W, Bureau C, Appenrodt B, et al.
J Hepatol
. 2012 Sep;
58(1):45-50.
PMID: 22940408
Background & Aims: In a recent randomized international clinical trial (RCT) in high-risk cirrhotic patients with acute variceal bleeding, the early use of transjugular intrahepatic portosystemic shunt (TIPS) was associated...
65.
Mihalache F, Hoblinger A, Acalovschi M, Sauerbruch T, Lammert F, Zimmer V
Hepatobiliary Pancreat Dis Int
. 2012 Aug;
11(4):412-7.
PMID: 22893469
Background: Micro-RNAs (miRNAs) are small, non-coding RNA species considered to fine-tune basic cellular functions by modulating target gene translation and/or mRNA stability. A common G/C polymorphism (rs2910164) in the precursor...
66.
Klein S, Klosel J, Schierwagen R, Korner C, Granzow M, Huss S, et al.
Lab Invest
. 2012 Aug;
92(10):1440-50.
PMID: 22890553
Hepatic myofibroblasts (MFB) show increased proliferation, migration and collagen production, which are crucial for hepatic fibrogenesis. Atorvastatin treatment inhibits proliferation, apoptosis and cytokine production of MFB in bile duct-ligated (BDL)...
67.
Nischalke H, Schmitz V, Luda C, Aldenhoff K, Berger C, Feldmann G, et al.
PLoS One
. 2012 Aug;
7(8):e42141.
PMID: 22879911
Introduction: It is a challenging task to distinguish between benign and malignant lesions in patients with biliary strictures. Here we analyze whether determination of target gene mRNA levels in intraductal...
68.
Klein S, van Beuge M, Granzow M, Beljaars L, Schierwagen R, Kilic S, et al.
J Hepatol
. 2012 Aug;
57(6):1220-7.
PMID: 22878469
Background & Aims: Rho-kinase activation mediates cell contraction and increases intrahepatic resistance and consequently portal pressure in liver cirrhosis. Systemic Rho-kinase inhibition decreases portal pressure in cirrhosis, but also arterial...
69.
Langhans B, Nischalke H, Arndt S, Braunschweiger I, Nattermann J, Sauerbruch T, et al.
PLoS One
. 2012 Aug;
7(7):e42094.
PMID: 22848715
Ribavirin improves outcomes of therapy in chronic hepatitis C but its mode of action has still remained unclear. Since ribavirin has been proposed to modulate the host's T cell responses,...
70.
Eisenhardt M, Glassner A, Kramer B, Korner C, Sibbing B, Kokordelis P, et al.
PLoS One
. 2012 Jul;
7(7):e38846.
PMID: 22792160
Background: In mouse models, natural killer (NK) cells have been shown to exert anti-fibrotic activity via killing of activated hepatic stellate cells (HSC). Chemokines and chemokine receptors critically modulate hepatic...