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Tilman Sauerbruch

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Articles 270
Citations 5003
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Recent Articles
41.
Jansen C, Eischeid H, Goertzen J, Schierwagen R, Anadol E, Strassburg C, et al.
PLoS One . 2014 Jul; 9(7):e103779. PMID: 25068403
Background: Circulating miRNA-34a is increased in blood of patients with different liver diseases when compared to healthy controls. However, the origin of miRNA-34a and its possible relationship with hemodynamics and...
42.
Nischalke H, Lutz P, Kramer B, Sohne J, Muller T, Rosendahl J, et al.
J Hepatol . 2014 Jun; 61(5):1073-9. PMID: 24946282
Background & Aims: The genetic background of alcoholic liver diseases and their complications are increasingly recognized. A common polymorphism in the neurocan (NCAN) gene, which is known to be expressed...
43.
Trebicka J, Wix C, von Heydebrand M, Hittatiya K, Reiberger T, Klein S, et al.
Liver Int . 2014 Jun; 35(4):1393-402. PMID: 24912856
Background & Aims: Patients with cirrhosis display hypocontractility of splanchnic vessels because of dysregulation of vasoactive proteins, such as decreased effect of RhoA/ROCK and increased activity of β-Arrestin-2 and eNOS....
44.
Raskopf E, Gonzalez Carmona M, Van Cayzeele C, Strassburg C, Sauerbruch T, Schmitz V
Biomed Res Int . 2014 Apr; 2014:712893. PMID: 24734240
Excessive ethanol consumption is one of the main causes of liver fibrosis. However, direct effects of ethanol exposure on endothelial cells and their contribution to fibrogenesis and metastasis were not...
45.
Lutz P, Parcina M, Bekeredjian-Ding I, Nischalke H, Nattermann J, Sauerbruch T, et al.
PLoS One . 2014 Apr; 9(4):e93909. PMID: 24714550
Background: Rifaximin is a non-absorbable antibiotic used to prevent relapses of hepatic encephalopathy which may also be a candidate for prophylaxis of spontaneous bacterial peritonitis (SBP). Aim: To detect the...
46.
Macias-Rodriguez R, Duarte-Rojo A, Cantu-Brito C, Sauerbruch T, Ruiz-Margain A, Trebicka J, et al.
Liver Int . 2014 Apr; 35(2):344-52. PMID: 24690075
Background & Aims: Factors other than elevated levels of ammonia may be implicated in hepatic encephalopathy (HE) pathophysiology, including abnormal cerebral haemodynamics. Transcranial Doppler ultrasonography (TCD) evaluates cerebrovascular structural integrity...
47.
Granzow M, Schierwagen R, Klein S, Kowallick B, Huss S, Linhart M, et al.
Hepatology . 2014 Mar; 60(1):334-48. PMID: 24619965
Unlabelled: Activation of the renin angiotensin system resulting in stimulation of angiotensin-II (AngII) type I receptor (AT1R) is an important factor in the development of liver fibrosis. Here, we investigated...
48.
Trebicka J, Krag A, Gansweid S, Schiedermaier P, Strunk H, Fimmers R, et al.
PLoS One . 2014 Jan; 8(12):e83341. PMID: 24386183
Background: TNFα levels are increased in liver cirrhosis even in the absence of infection, most likely owing to a continuous endotoxin influx into the portal blood. Soluble TNFα receptors (sTNFR...
49.
Sauerbruch T
Liver Int . 2013 Dec; 34(1):4-5. PMID: 24321057
No abstract available.
50.
Liedtke C, Luedde T, Sauerbruch T, Scholten D, Streetz K, Tacke F, et al.
Fibrogenesis Tissue Repair . 2013 Nov; 6(1):19. PMID: 24274743
Liver fibrosis is defined as excessive extracellular matrix deposition and is based on complex interactions between matrix-producing hepatic stellate cells and an abundance of liver-resident and infiltrating cells. Investigation of...