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Tilman Heinrich

Explore the profile of Tilman Heinrich including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 260
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Recent Articles
11.
Mikus G, Heinrich T, Bodigheimer J, Roder C, Matthee A, Weiss J, et al.
J Clin Pharmacol . 2017 Feb; 57(7):899-905. PMID: 28194792
This study aimed to assess whether a single oral dose of the nonnucleoside reverse transcriptase inhibitor efavirenz can alter CYP3A in vivo. In 12 healthy participants individual CYP3A activity was...
12.
Heinrich T, Nanda I, Rehn M, Zollner U, Ernestus K, Wirth C, et al.
Cytogenet Genome Res . 2015 Apr; 145(1):25-8. PMID: 25823796
Achondrogenesis type II is an autosomal-dominant disease leading to severe micromelic dwarfism. Here, we report on the postmortem identification of a de novo heterozygous mutation in the COL2A1 gene (c.1529G>A,...
13.
Roessler J, Ammerpohl O, Gutwein J, Steinemann D, Schlegelberger B, Weyer V, et al.
Epigenomics . 2014 Oct; 7(2):187-99. PMID: 25347269
Background: Aberrations in DNA methylation patterns are well-described in human malignancies. However, the existence of the 'CpG island methylator phenotype' (CIMP) in human breast cancer is still controversial. Materials &...
14.
Rhiem K, Engel C, Graeser M, Zachariae S, Kast K, Kiechle M, et al.
Breast Cancer Res . 2012 Dec; 14(6):R156. PMID: 23216834
Introduction: While it has been reported that the risk of contralateral breast cancer in patients from BRCA1 or BRCA2 positive families is elevated, little is known about contralateral breast cancer...
15.
Burhenne J, Matthee A, Pasakova I, Roder C, Heinrich T, Haefeli W, et al.
Antimicrob Agents Chemother . 2010 Jul; 54(10):4185-91. PMID: 20660679
Intracellular concentrations of antiretroviral drugs in peripheral blood mononuclear cells (PBMCs) are an important determinant of therapeutic success. In vitro data indicate that efavirenz induces several ATP-binding cassette (ABC) transporters,...
16.
Heinrich T, Heidt H, Hafner V, Schmidt-Gayk H, Jenetzky E, Walter-Sack I, et al.
Nephrol Dial Transplant . 2008 Apr; 23(9):2861-7. PMID: 18388122
Background: Under steady-state conditions urinary calcium (Ca) excretion corresponds to the Ca load in healthy subjects. However, in chronic haemodialysis patients reliable data on Ca load are not available. In...
17.
Storch C, Klimm H, Heinrich T, Haefeli W, Weiss J
Naunyn Schmiedebergs Arch Pharmacol . 2007 Jul; 376(1-2):135-43. PMID: 17653693
Several studies have demonstrated that the adenosine triphosphate-binding cassette transporter P-glycoprotein (P-gp) is at least partly located in cholesterol- and sphingolipid-enriched parts of the plasma membrane called "lipid rafts" and...
18.
Roder C, Heinrich T, Gehrig A, Mikus G
AIDS . 2007 Jun; 21(10):1390-1. PMID: 17545727
No abstract available.
19.
Heinrich T, Prowald C, Friedl R, Gottwald B, Kalb R, Neveling K, et al.
Eur J Pediatr . 2006 Jan; 165(4):250-7. PMID: 16411093
Ataxia telangiectasia (AT) is an autosomal recessive multisystem disorder with increased radiosensitivity and cancer susceptibility. The responsible gene (ATM) consists of 66 exons and a coding region of 9171 bp...