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Tikam Chand Dakal

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Articles 58
Citations 936
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Recent Articles
11.
Dakal T, Bhushan R, Xu C, Gadi B, Cameotra S, Yadav V, et al.
MedComm (2020) . 2024 Sep; 5(10):e710. PMID: 39309691
Cancer stem cells (CSCs) are widely acknowledged as the drivers of tumor initiation, epithelial-mesenchymal transition (EMT) progression, and metastasis. Originating from both hematologic and solid malignancies, CSCs exhibit quiescence, pluripotency,...
12.
Dakal T, Dhakar R, Beura A, Moar K, Maurya P, Sharma N, et al.
Pathol Res Pract . 2024 Sep; 262:155567. PMID: 39232287
Modern cancer research depends heavily on the identification and validation of biomarkers because they provide important information about the diagnosis, prognosis, and response to treatment of the cancer. This review...
13.
Wang Y, Qin J, Sharma A, Dakal T, Wang J, Pan T, et al.
Cancer Cell Int . 2024 Sep; 24(1):305. PMID: 39227952
RGS (Regulator of G protein signaling) proteins have long captured the fascination of researchers due to their intricate involvement across a wide array of signaling pathways within cellular systems. Their...
14.
Dakal T, Kakde G, Maurya P
Metab Brain Dis . 2024 Aug; 39(8):1591-1611. PMID: 39180605
The mostly aggressive and extremely malignant type of central nervous system is Glioblastoma (GBM), which is characterized by an extremely short average survival time of lesser than 16 months. The...
15.
Dakal T, Choudhary K, Tiwari I, Yadav V, Maurya P, Sharma N
Neuroscience . 2024 Jun; 552:126-141. PMID: 38936458
The mammalian brain's complete dependence on oxygen for ATP production makes it highly susceptible to hypoxia, at high altitudes or in clinical scenarios including anemia or pulmonary disease. Hypoxia plays...
16.
Sharma N, Dwivedi P, Bhushan R, Maurya P, Kumar A, Dakal T
Funct Integr Genomics . 2024 Jun; 24(4):117. PMID: 38918231
The role of messenger RNA (mRNA) in biological systems is extremely versatile. However, it's extremely short half-life poses a fundamental restriction on its application. Moreover, the translation efficiency of mRNA...
17.
Zhang X, Fan Y, Jing R, Getu M, Chen W, Zhang W, et al.
Mil Med Res . 2024 Jun; 11(1):35. PMID: 38835066
Neuroendocrine neoplasms (NENs) are highly heterogeneous and potentially malignant tumors arising from secretory cells of the neuroendocrine system. Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are the most common subtype of NENs. Historically,...
18.
Dakal T, Dhabhai B, Pant A, Moar K, Chaudhary K, Yadav V, et al.
MedComm (2020) . 2024 Jun; 5(6):e582. PMID: 38827026
Cancer, being the most formidable ailment, has had a profound impact on the human health. The disease is primarily associated with genetic mutations that impact oncogenes and tumor suppressor genes...
19.
Dakal T, George N, Xu C, Suravajhala P, Kumar A
Cancers (Basel) . 2024 May; 16(9). PMID: 38730579
TIICs are critical components of the TME and are used to estimate prognostic and treatment responses in many malignancies. TIICs in the tumor microenvironment are assessed and quantified by categorizing...
20.
Deepika , Dakal T, Sharma N, Ranga V, Maurya P
Rejuvenation Res . 2024 Feb; 27(1):3-16. PMID: 38308480
The therapeutic application of flavonoids in the management of infectious diseases, cancers, chronic wounds, aging, and neurodegenerative disorders has been well documented in scientific literature. The citric flavonoid naringenin comes...