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Tiffany Porta Siegel

Explore the profile of Tiffany Porta Siegel including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 266
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Recent Articles
1.
Kaufmann M, Vaysse P, Savage A, Kooreman L, Janssen N, Varma S, et al.
Br J Cancer . 2024 Sep; 131(8):1298-1308. PMID: 39294437
Background: While REIMS technology has successfully been demonstrated for the histological identification of ex-vivo breast tumor tissues, questions regarding the robustness of the approach and the possibility of tumor molecular...
2.
Nauta S, Greven J, Hofman M, Mohren R, Meesters D, Mockel D, et al.
J Am Soc Mass Spectrom . 2024 Apr; 35(6):1184-1196. PMID: 38679918
Bone fracture healing is a complex process in which specific molecular knowledge is still lacking. The citrulline-arginine-nitric oxide metabolism is one of the involved pathways, and its enrichment via citrulline...
3.
Vaysse P, van den Hout M, Engelen S, Keymeulen K, Bemelmans M, Heeren R, et al.
J Surg Oncol . 2023 Dec; 129(3):499-508. PMID: 38050894
Background: Soft tissue sarcomas (STS) constitute a heterogeneous group of rare tumor entities. Treatment relies on challenging patient-tailored surgical resection. Real-time intraoperative lipid profiling of electrosurgical vapors by rapid evaporative...
4.
Hadavi D, Tosheva I, Porta Siegel T, Cuypers E, Honing M
Front Bioeng Biotechnol . 2023 Jun; 11:1197760. PMID: 37284240
Three-dimensional (3D) cell cultures, including organ-on-a-chip (OOC) devices, offer the possibility to mimic human physiology conditions better than 2D models. The organ-on-a-chip devices have a wide range of applications, including...
5.
Kaufmann M, Vaysse P, Savage A, Amgheib A, Marton A, Manoli E, et al.
Metabolites . 2022 Nov; 12(11). PMID: 36422272
Rapid evaporative ionization mass spectrometry (REIMS) is a direct tissue metabolic profiling technique used to accurately classify tissues using pre-built mass spectral databases. The reproducibility of the analytical equipment, methodology...
6.
Lamont L, Hadavi D, Bowman A, Flinders B, Cooper-Shepherd D, Palmer M, et al.
Rapid Commun Mass Spectrom . 2022 Nov; 37(5):e9439. PMID: 36415963
Rationale: Isomeric separation of prostanoids is often a challenge and requires chromatography and time-consuming sample preparation. Multiple prostanoid isomers have distinct in vivo functions crucial for understanding the inflammation process,...
7.
Van Hese L, de Vleeschouwer S, Theys T, Lariviere E, Solie L, Sciot R, et al.
J Mass Spectrom Adv Clin Lab . 2022 May; 24:80-89. PMID: 35572786
Introduction: The main goal of brain tumour surgery is to maximize tumour resection while avoiding neurological deficits. Accurate characterization of tissue and delineation of resection margins are, therefore, essential to...
8.
Vaysse P, Demers I, van den Hout M, van de Worp W, Anthony I, Baijens L, et al.
Anal Chem . 2022 May; 94(19):6939-6947. PMID: 35503862
Radical resection for patients with oral cavity cancer remains challenging. Rapid evaporative ionization mass spectrometry (REIMS) of electrosurgical vapors has been reported for real-time classification of normal and tumor tissues...
9.
Groven R, Nauta S, Gruisen J, Claes B, Greven J, van Griensven M, et al.
Front Chem . 2022 Mar; 9:780626. PMID: 35309042
Fracture healing is a complex process, involving cell-cell interactions, various cytokines, and growth factors. Although fracture treatment improved over the last decades, a substantial part of all fractures shows delayed...
10.
Hadavi D, Borzova M, Porta Siegel T, Honing M
Anal Chim Acta . 2022 Mar; 1200:339617. PMID: 35256146
Bile acids are steroid compounds involved in biological mechanisms of neurodegenerative diseases making them potential biomarkers for diagnosis or treatment. These compounds exist as structural and conformational isomers, which hinder...