Tianrong Xun
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Explore the profile of Tianrong Xun including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
159
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0
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Recent Articles
1.
Su H, Xiao S, Liang Z, Xun T, Zhang J, Yang X
Front Pharmacol
. 2025 Feb;
15:1475222.
PMID: 39911832
Background: In contrast to previous network meta-analysis using classical frequentist methods, we evaluated the efficacy and safety of six frequently-used biologics through a Bayesian method. Methods: Web of Science, Scopus,...
2.
Xun T, Zhang M, Wei S, Zhao C, Lin Z, Feng H, et al.
Eur J Pharm Sci
. 2024 Jun;
200:106829.
PMID: 38866111
Drug-induced liver injury (DILI) is prevalent in the treatment of chronic kidney disease (CKD). Advanced oxidation protein products (AOPPs) are markers of CKD progression and participate in the occurrence and...
3.
Zhao J, Zhao C, Xun T, Wang X, Wei S, Ye C, et al.
Drug Des Devel Ther
. 2024 Jan;
18:13-28.
PMID: 38205394
Purpose: This study aims to investigate the effects of Huang Gan formula (HGF), a Chinese herbal prescription used for chronic kidney disease (CKD), on the regulation of the gut microbiota...
4.
Li X, Xun T, Xu H, Pang X, Yang B, Wang J, et al.
Mar Drugs
. 2023 Jun;
21(6).
PMID: 37367651
Based on the marine natural products piperafizine B, XR334, and our previously reported compound , fourteen novel 3,6-diunsaturated 2,5-diketopiperazine (2,5-DKP) derivatives (, , -, -), together with two known ones...
5.
Xun T, Rong Y, Lv B, Tian J, Zhang Q, Yang X
Front Pharmacol
. 2023 May;
14:1165950.
PMID: 37251310
Voriconazole (VOR) is combined with atorvastatin (ATO) to treat fungal infections in patients with dyslipidemia in clinical practice. However, the pharmacokinetic interactions and potential mechanisms between them are unknown. Therefore,...
6.
Wang X, Rao J, Tan Z, Xun T, Zhao J, Yang X
Front Pharmacol
. 2022 Nov;
13:1043836.
PMID: 36353494
Cytochrome P450 (CYP450) enzymes are membrane-bound blood proteins that are vital to drug detoxification, cell metabolism, and homeostasis. CYP450s belonging to CYP families 1-3 are responsible for nearly 80% of...
7.
Xun T, Lin Z, Zhang M, Mo L, Chen Y, Wang X, et al.
Toxicol Appl Pharmacol
. 2022 Jun;
449:116140.
PMID: 35753429
The unpredictable pharmacokinetics of non-renal cleared drugs in chronic kidney disease (CKD) patients is associated with the activity of drug transporters. However, the mechanisms underlying regulation of drug transporters are...
8.
Xun T, Lin Z, Wang X, Zhan X, Feng H, Gan D, et al.
Lab Invest
. 2021 May;
101(9):1197-1209.
PMID: 34031539
Uremic toxin accumulation is one possible reason for alterations in hepatic drug metabolism in patients with chronic kidney disease (CKD). However, the types of uremic toxins and underlying mechanisms are...
9.
Wang X, Ye C, Xun T, Mo L, Tong Y, Ni W, et al.
Front Pharmacol
. 2021 May;
12:663325.
PMID: 33995087
The antifungal agent voriconazole (VRC) exhibits extreme inter-individual and intra-individual variation in terms of its clinical efficacy and toxicity. Inflammation, as reflected by C-reactive protein (CRP) concentrations, significantly affects the...
10.
Wu S, Mo L, Ye C, Xun T, Wang X, Lv B, et al.
J Pharm Pharmacol
. 2021 Mar;
73(8):1039-1048.
PMID: 33749788
Objectives: The aim of the study was to explore the effect of total glucosides of paeony (TGP) and Tripterygium wilfordii polyglycosides (TWP) on erythrocyte methotrexate polyglutamates (MTXPGs), the metabolites of...