Tiak Ju Tan
Overview
Explore the profile of Tiak Ju Tan including associated specialties, affiliations and a list of published articles.
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8
Citations
17
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Recent Articles
1.
Abdu S, Xia J, Yuan H, Tan T, Layhadi J, Shamji M, et al.
Allergy
. 2025 Jan;
PMID: 39829150
Background: Alarmin cytokine IL-25 promotes type 2 inflammatory responses in disorders such as asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) and known targets include ILC2 and Th2 cells. However,...
2.
Chew E, Liu Z, Li Z, Chung S, Lian M, Tandiono M, et al.
Nat Aging
. 2024 Nov;
5(2):205-218.
PMID: 39572736
Parkinson's disease (PD) is an incurable, progressive and common movement disorder that is increasing in incidence globally because of population aging. We hypothesized that the landscape of rare, protein-altering variants...
3.
Shah M, Layhadi J, Hourcade D, Fulton W, Tan T, Dunham D, et al.
Allergy
. 2024 Jul;
79(9):2502-2523.
PMID: 39033312
Background: During the COVID-19 pandemic, novel nanoparticle-based mRNA vaccines were developed. A small number of individuals developed allergic reactions to these vaccines although the mechanisms remain undefined. Methods: To understand...
4.
Walters B, Tan T, Tan C, Dube C, Lee K, Koh J, et al.
J Cell Sci
. 2023 Jun;
136(12).
PMID: 37259855
The mammalian epidermis undergoes constant renewal, replenished by a pool of stem cells and terminal differentiation of their progeny. This is accompanied by changes in gene expression and morphology that...
5.
Layhadi J, Moya R, Tan T, Lenormand M, Sharif H, Parkin R, et al.
J Allergy Clin Immunol
. 2023 Jan;
151(5):1357-1370.e9.
PMID: 36649758
Background: Immunologic mechanism of action of allergoids remains poorly understood. Previous models of allergenicity and immunogenicity have yielded suboptimal knowledge of these immunotherapeutic vaccine products. Novel single-cell RNA sequencing technology...
6.
Pablo-Torres C, Izquierdo E, Tan T, Obeso D, Layhadi J, Sanchez-Solares J, et al.
Allergy
. 2022 Dec;
78(5):1319-1332.
PMID: 36527294
Background: Mechanisms causing the onset and perpetuation of inflammation in severe allergic patients remain unknown. Our previous studies suggested that severe allergic inflammation is linked to platelet dysfunction. Methods: Platelet-rich...
7.
Tan T, Delgado-Dolset M, Escribese M, Barber D, Layhadi J, Shamji M
Allergol Select
. 2022 Dec;
6:267-275.
PMID: 36457722
Allergic rhinitis is an IgE-mediated inflammation that remains a clinical challenge, affecting 40% of the UK population with a wide range of severity from nasal discomfort to life-threatening anaphylaxis. It...
8.
Dube C, Ong Y, Wemyss K, Krishnan S, Tan T, Janela B, et al.
Front Immunol
. 2022 Jul;
13:943159.
PMID: 35874681
Ageing-related delays and dysregulated inflammation in wound healing are well-documented in both human and animal models. However, cellular and molecular changes underlying this impairment in healing progression are not fully...
9.
Tan T, Layhadi J, Shamji M
Allergy Asthma Proc
. 2022 Jul;
43(4):254-259.
PMID: 35818151
There are currently no biomarkers that can accurately predict clinical outcomes and segregate responders from nonresponders in allergen immunotherapy (AIT). Therefore, identifying a reliable predictive biomarker is essential to enable...