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Thordur Sigmundsson

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Recent Articles
1.
Didriksen M, Nawaz M, Dowsett J, Bell S, Erikstrup C, Pedersen O, et al.
Commun Biol . 2020 Nov; 3(1):703. PMID: 33239738
Restless legs syndrome (RLS) is a common neurological sensorimotor disorder often described as an unpleasant sensation associated with an urge to move the legs. Here we report findings from a...
2.
Grool A, Geerlings M, Sigurdsson S, Eiriksdottir G, Jonsson P, Garcia M, et al.
Neurology . 2014 Apr; 82(18):1628-35. PMID: 24739783
Objective: We aimed to investigate the relation between apathy symptoms and structural brain changes on MRI, including white matter lesions (WMLs) and atrophy, in a large cohort of older persons....
3.
Greenwood K, Wykes T, Sigmundsson T, Landau S, Morris R
J Int Neuropsychol Soc . 2011 Apr; 17(3):474-84. PMID: 21473804
Neuropsychological models propose qualitatively distinct planning impairments in the psychomotor poverty and disorganization syndromes in schizophrenia. It was proposed that poor plan initiation in psychomotor poverty would lead to longer...
4.
Haraldsson H, Ettinger U, Magnusdottir B, Sigmundsson T, Sigurdsson E, Ingason A, et al.
Psychiatry Res . 2009 Aug; 169(2):173-5. PMID: 19647329
The association between the catechol-O-methyltransferase (COMT) val(158)met polymorphism (rs4680) and smooth pursuit eye movements (SPEM) was investigated in 110 schizophrenia patients and 96 controls. Patients had lower steady-state pursuit gain...
5.
Haraldsson H, Ettinger U, Magnusdottir B, Ingason A, Hutton S, Sigmundsson T, et al.
Eur Arch Psychiatry Clin Neurosci . 2009 Jul; 260(1):77-85. PMID: 19575259
Neuregulin-1 (NRG-1) is a putative susceptibility gene for schizophrenia but the neurocognitive processes that may involve NRG-1 in schizophrenia are unknown. Deficits in antisaccade (AS) and smooth pursuit eye movements...
6.
Stefansson H, Ophoff R, Steinberg S, Andreassen O, Cichon S, Rujescu D, et al.
Nature . 2009 Jul; 460(7256):744-7. PMID: 19571808
Schizophrenia is a complex disorder, caused by both genetic and environmental factors and their interactions. Research on pathogenesis has traditionally focused on neurotransmitter systems in the brain, particularly those involving...
7.
Trotti L, Bliwise D, Greer S, Sigurdsson A, Gudmundsdottir G, Wessel T, et al.
Sleep Med . 2008 Nov; 10(6):668-71. PMID: 19022704
Objective: Night-to-night variability of periodic leg movements (PLMs) in restless legs syndrome (RLS) was examined to define the range of intra-subject values, impact upon diagnosing RLS, and clinical correlates. Methods:...
8.
Rujescu D, Ingason A, Cichon S, Pietilainen O, Barnes M, Toulopoulou T, et al.
Hum Mol Genet . 2008 Oct; 18(5):988-96. PMID: 18945720
Deletions within the neurexin 1 gene (NRXN1; 2p16.3) are associated with autism and have also been reported in two families with schizophrenia. We examined NRXN1, and the closely related NRXN2...
9.
Lublin H, Haug H, Koponen H, Sigmundsson T, Kolb S
World J Biol Psychiatry . 2008 Sep; 10(4 Pt 3):710-8. PMID: 18803070
The efficacy, safety and tolerability of ziprasidone versus the comparators olanzapine, risperidone or quetiapine were investigated in adult patients with chronic schizophrenia, schizoaffective and schizophreniform disorders, with lack of efficacy...
10.
Greenwood K, Morris R, Sigmundsson T, Landau S, Wykes T
J Int Neuropsychol Soc . 2008 Sep; 14(5):782-92. PMID: 18764973
This study reports the executive function profile in people with schizophrenia, with a simultaneous comparison of chronicity and of those with predominately disorganization versus psychomotor poverty symptoms. The patients were...