Thomas Zillinger
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Explore the profile of Thomas Zillinger including associated specialties, affiliations and a list of published articles.
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47
Citations
2497
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Recent Articles
1.
Farrukee R, Schwab L, Barnes J, Brooks A, Londrigan S, Hartmann G, et al.
Sci Rep
. 2024 Jun;
14(1):13524.
PMID: 38866913
Myxovirus resistance (Mx) proteins are products of interferon stimulated genes (ISGs) and Mx proteins of different species have been reported to mediate antiviral activity against a number of viruses, including...
2.
Heinz J, Hinke D, Maimaitili M, Wang J, Sabli I, Thomsen M, et al.
J Med Virol
. 2024 May;
96(6):e29690.
PMID: 38804180
Autophagy is a degradational pathway with pivotal roles in cellular homeostasis and survival, including protection of neurons in the central nervous system (CNS). The significance of autophagy as antiviral defense...
3.
Condic M, Rohr A, Riemann S, Staerk C, Ayub T, Doeser A, et al.
Cancer Res Commun
. 2024 Feb;
4(3):861-875.
PMID: 38407373
Significance: Immunoprofiling in VSCC reveals subtypes with distinct clinical and biological behavior. Of these, the macrophage-rich VSCC subtype is characterized by poor clinical outcome and increased VEGF-A expression, providing a...
4.
Rosing S, Ullrich F, Meisterfeld S, Schmidt F, Mlitzko L, Croon M, et al.
Nat Commun
. 2024 Feb;
15(1):1534.
PMID: 38378748
Myotonic dystrophy type 2 (DM2) is a tetranucleotide CCTG repeat expansion disease associated with an increased prevalence of autoimmunity. Here, we identified an elevated type I interferon (IFN) signature in...
5.
A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA
de Regt A, Anand K, Ciupka K, Bender F, Gatterdam K, Putschli B, et al.
Nucleic Acids Res
. 2023 Oct;
51(21):11893-11910.
PMID: 37831086
RIG-I is a cytosolic receptor of viral RNA essential for the immune response to numerous RNA viruses. Accordingly, RIG-I must sensitively detect viral RNA yet tolerate abundant self-RNA species. The...
6.
Kapp F, Kretschmer S, Beckmann C, Wasch L, Molitor A, Carapito R, et al.
Clin Immunol
. 2023 Sep;
256:109777.
PMID: 37741518
C-terminal variants in CDC42 encoding cell division control protein 42 homolog underlie neonatal-onset cytopenia, autoinflammation, rash, and hemophagocytic lymphohistiocytosis (NOCARH). Pyrin inflammasome hyperactivation has been shown to contribute to disease...
7.
Tsukamoto Y, Hiono T, Yamada S, Matsuno K, Faist A, Claff T, et al.
Science
. 2023 Feb;
379(6632):586-591.
PMID: 36758070
Orthomyxo- and bunyaviruses steal the 5' cap portion of host RNAs to prime their own transcription in a process called "cap snatching." We report that RNA modification of the cap...
8.
Complexing CpG adjuvants with cationic liposomes enhances vaccine-induced formation of liver T cells
Valencia-Hernandez A, Zillinger T, Ge Z, Tan P, Cozijnsen A, McFadden G, et al.
Vaccine
. 2023 Jan;
41(5):1094-1107.
PMID: 36609029
Tissue resident memory T cells (T cells) can provide effective tissue surveillance and can respond rapidly to infection. Vaccination strategies aimed at generating T cells have shown promise against a...
9.
Kessler N, Viehmann S, Krollmann C, Mai K, Kirschner K, Luksch H, et al.
J Exp Med
. 2022 Nov;
219(12).
PMID: 36367753
No abstract available.
10.
Schumann T, Costas Ramon S, Schubert N, Mayo M, Hega M, Maser K, et al.
J Exp Med
. 2022 Nov;
220(1).
PMID: 36346347
Defects in nucleic acid metabolizing enzymes can lead to spontaneous but selective activation of either cGAS/STING or RIG-like receptor (RLR) signaling, causing type I interferon-driven inflammatory diseases. In these pathophysiological...