Thomas W Klein
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Explore the profile of Thomas W Klein including associated specialties, affiliations and a list of published articles.
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34
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1372
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Recent Articles
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Reich R, Lengacher C, Klein T, Newton C, Shivers S, Ramesar S, et al.
Biol Res Nurs
. 2017 May;
19(4):456-464.
PMID: 28460534
Purpose: The purpose of this substudy of a large randomized controlled trial was to evaluate the efficacy of the Mindfulness-Based Stress Reduction (Breast Cancer) (MBSR[BC]) program compared to usual care...
3.
Williams J, Klein T, Goldberger B, Sleasman J, Mackman N, Goodenow M
J Inflamm (Lond)
. 2015 Jun;
12:39.
PMID: 26085816
Background: Immunomodulatory effects in humans of Δ(9-)Tetrahydrocannabinol (THC), the psychoactive component of marijuana are controversial. Tissue factor (TF), the activator of the extrinsic coagulation cascade, is increased on circulating activated...
4.
Williams J, Appelberg S, Goldberger B, Klein T, Sleasman J, Goodenow M
J Neuroimmune Pharmacol
. 2014 Feb;
9(3):369-79.
PMID: 24562630
The major psychoactive component of marijuana, Δ(9)-tetrahydrocannabinol (THC), also acts to suppress inflammatory responses. Receptors for THC, CB1, CB2, and GPR55, are differentially expressed on multiple cell types including monocytes...
5.
Reich R, Lengacher C, Kip K, Shivers S, Schell M, Shelton M, et al.
Biol Res Nurs
. 2014 Jan;
16(4):429-37.
PMID: 24477514
Researchers focused on patient-centered medicine are increasingly trying to identify baseline factors that predict treatment success. Because the quantity and function of lymphocyte subsets change during stress, we hypothesized that...
6.
Newton C, Klein T
J Neuroimmune Pharmacol
. 2012 May;
7(3):591-8.
PMID: 22552780
Marijuana cannabinoids such as Δ(9)-tetrahydrocannabinol (THC) have been shown in experimental systems to bias T helper immunity towards Th2 and away from Th1. This effect if broadly applicable to humans...
7.
Lengacher C, Kip K, Post-White J, Fitzgerald S, Newton C, Barta M, et al.
Biol Res Nurs
. 2011 Nov;
15(1):37-47.
PMID: 22084404
Objectives: This randomized controlled trial was conducted to examine immune recovery following breast cancer (BC) therapy and evaluate the effect of mindfulness-based stress reduction therapy (MBSR) on immune recovery with...
8.
Sherwood T, Nong L, Agudelo M, Newton C, Widen R, Klein T
J Neuroimmune Pharmacol
. 2009 Sep;
4(4):476-88.
PMID: 19757078
Marijuana cannabinoids, the endocannabinoids, and cannabinoid cell receptors have been shown to play important roles in immune regulation particularly as potent modulators of anti-inflammatory cytokines. The predominant cannabinoid receptor involved...
9.
Lengacher C, Johnson-Mallard V, Post-White J, Moscoso M, Jacobsen P, Klein T, et al.
Psychooncology
. 2009 Feb;
18(12):1261-72.
PMID: 19235193
Objectives: Considerable morbidity persists among survivors of breast cancer (BC) including high levels of psychological stress, anxiety, depression, fear of recurrence, and physical symptoms including pain, fatigue, and sleep disturbances,...
10.
Chou P, Newton C, Perkins I, Friedman H, Klein T
DNA Cell Biol
. 2008 Sep;
27(12):637-48.
PMID: 18821847
Bacillus anthracis produces lethal toxin (LT) and edema toxin (ET), and they suppress the function of LPS-stimulated dendritic cells (DCs). Because DCs respond differently to various microbial stimuli, we compared...