Thomas W Dunlop
Overview
Explore the profile of Thomas W Dunlop including associated specialties, affiliations and a list of published articles.
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16
Citations
452
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Recent Articles
1.
Rauhala L, Hamalainen L, Dunlop T, Pehkonen P, Bart G, Kokkonen M, et al.
Toxicol In Vitro
. 2015 Sep;
30(1 Pt B):462-75.
PMID: 26391144
The moisturizing and potentially protective properties of the organic osmolyte betaine (trimethylglycine) have made it an attractive component for skin care products. Its wide use despite the lack of comprehensive...
2.
Mykkanen O, Huotari A, Herzig K, Dunlop T, Mykkanen H, Kirjavainen P
PLoS One
. 2014 Dec;
9(12):e114790.
PMID: 25501421
Background: Low-grade metabolic inflammation and hypertension are primary mechanisms involved in obesity-associated adverse health effects. Berries, especially Nordic wild blueberries (hereafter referred to as bilberries), represent an important source of...
3.
Turunen M, Dunlop T, Carlberg C, Vaisanen S
Nucleic Acids Res
. 2007 Apr;
35(8):2734-47.
PMID: 17426122
The human 25-hydroxyvitamin D3 (25(OH)D3) 1alpha-hydroxylase, which is encoded by the CYP27B1 gene, catalyzes the metabolic activation of the 25(OH)D3 into 1alpha,25-dihydroxyvitamin D3 (1alpha,25(OH)2D3), the most biologically potent vitamin D3...
4.
Carlberg C, Dunlop T, Saramaki A, Sinkkonen L, Matilainen M, Vaisanen S
J Steroid Biochem Mol Biol
. 2007 Jan;
103(3-5):338-43.
PMID: 17234401
An essential prerequisite for the direct modulation of transcription by 1alpha,25-dihydroxy vitamin D(3) (1alpha,25(OH)(2)D(3)) is the location of at least one activated vitamin D receptor (VDR) protein close to the...
5.
Degenhardt T, Matilainen M, Herzig K, Dunlop T, Carlberg C
J Biol Chem
. 2006 Oct;
281(51):39607-19.
PMID: 17062566
Insulin-like growth factor-binding protein 1 (IGFBP-1) is a biomarker for metabolic and hyperproliferative diseases. At the same time, the nuclear receptors peroxisome proliferator-activated receptors (PPARs) are known for their critical...
6.
Carlberg C, Dunlop T
Anticancer Res
. 2006 Aug;
26(4A):2637-45.
PMID: 16886674
The vitamin D receptor (VDR), the nuclear receptor for 1alpha,25-dihydroxyvitamin D3 (1alpha,25(OH)2D3), controls gene expression by binding discrete DNA sequences in promoter regions of target genes, referred to as 1alpha,25(OH)2D3...
7.
An integrated biological approach to nuclear receptor signaling in physiological control and disease
Carlberg C, Dunlop T
Crit Rev Eukaryot Gene Expr
. 2006 Apr;
16(1):1-22.
PMID: 16584379
The nuclear receptors (NRs)--vitamin D receptor (VDR); peroxisome proliferator-activated receptor (PPAR) alpha, delta, gamma; and pregnane X receptor (PXR)--act as sensors for various molecules encountered by the body on a...
8.
Kobayashi H, Kromminga A, Dunlop T, Tychsen B, Conrad F, Suzuki N, et al.
FASEB J
. 2005 Jul;
19(12):1710-2.
PMID: 16030176
Since mammalian skin expresses the enzymatic apparatus for melatonin synthesis, it may be an extrapineal site of melatonin synthesis. However, evidence is still lacking that this is really the case...
9.
Vaisanen S, Dunlop T, Sinkkonen L, Frank C, Carlberg C
J Mol Biol
. 2005 May;
350(1):65-77.
PMID: 15919092
The vitamin D3 24-hydroxylase gene (CYP24) is one of the most strongly induced genes known. Despite this, its induction by the hormone 1alpha,25-dihydroxyvitamin D3 (1alpha,25OH2D3) has been characterized only partially....
10.
Dunlop T, Vaisanen S, Frank C, Molnar F, Sinkkonen L, Carlberg C
J Mol Biol
. 2005 May;
349(2):248-60.
PMID: 15890193
Peroxisome proliferator-activated receptor (PPAR) delta is the most widely expressed member of the PPAR family of nuclear receptor fatty acid sensors. Real-time PCR analysis of breast and prostate cancer cell...