Thomas Trimaille
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Explore the profile of Thomas Trimaille including associated specialties, affiliations and a list of published articles.
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29
Citations
168
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Recent Articles
1.
Trimaille T, Verrier B
Pharmaceutics
. 2023 Oct;
15(10).
PMID: 37896241
Historically used for the delivery of hydrophobic drugs through core encapsulation, amphiphilic copolymer micelles have also more recently appeared as potent nano-systems to deliver protein and peptide therapeutics. In addition...
2.
Ayari-Riabi S, Ben Khalaf N, Bouhaouala-Zahar B, Verrier B, Trimaille T, Benlasfar Z, et al.
Molecules
. 2022 Dec;
27(24).
PMID: 36557812
Leishmaniasis is the 3rd most challenging vector-borne disease after malaria and lymphatic filariasis. Currently, no vaccine candidate is approved or marketed against leishmaniasis due to difficulties in eliciting broad immune...
3.
Lamrayah M, Phelip C, Coiffier C, Lacroix C, Willemin T, Trimaille T, et al.
Pharmaceutics
. 2022 Jan;
14(1).
PMID: 35057003
Micelles from amphiphilic polylactide-block-poly(-acryloxysuccinimide---vinylpyrrolidone) (PLA-b-P(NAS--NVP)) block copolymers of 105 nm in size were characterized and evaluated in a vaccine context. The micelles were non-toxic in vitro (both in dendritic cells...
4.
Fouquet T, Amalian J, Aniel N, Carvin-Sergent I, Issa S, Poyer S, et al.
Anal Chem
. 2021 Aug;
93(35):12041-12048.
PMID: 34431672
Because of its speed, sensitivity, and ability to scrutinize individual species, mass spectrometry (MS) has become an essential tool in analytical strategies aimed at studying the degradation behavior of polyesters....
5.
Gigmes D, Trimaille T
Adv Colloid Interface Sci
. 2021 Jul;
294:102483.
PMID: 34274723
Micelles from self-assembled amphiphilic copolymers are highly attractive in drug delivery, due to their small size and hydrophilic stealth corona allowing prolonged lifetimes in the bloodstream and thus improved drug...
6.
Bonnet M, Alluin O, Trimaille T, Gigmes D, Marqueste T, Decherchi P
ACS Omega
. 2020 May;
5(18):10247-10259.
PMID: 32426581
Spinal cord injury is a main health issue, leading to multiple functional deficits with major consequences such as motor and sensitive impairment below the lesion. To date, all repair strategies...
7.
Tebong Mbah V, Pertici V, Lacroix C, Verrier B, Stipa P, Gigmes D, et al.
Polymers (Basel)
. 2020 Apr;
12(4).
PMID: 32316376
Thermoresponsive poly(N-isopropylacrylamide) (PNIPAAm)-based injectable hydrogels represent highly attractive materials in tissue engineering and drug/vaccine delivery but face the problem of long-term bioaccumulation due to non-degradability. In this context, we developed...
8.
Lacroix C, Humanes A, Coiffier C, Gigmes D, Verrier B, Trimaille T
Pharm Res
. 2020 Jan;
37(2):30.
PMID: 31915939
Purpose: mRNA has recently emerged as a potent therapeutics and requires safe and effective delivery carriers, particularly prone to address its issues of poor stability and escape from endosomes. In...
9.
Bonnet M, Trimaille T, Brezun J, Feron F, Gigmes D, Marqueste T, et al.
Mater Sci Eng C Mater Biol Appl
. 2019 Nov;
107:110354.
PMID: 31761180
In line with experiments showing that implanted hydrogels are promising tools, we designed and injected, after a C2 spinal cord hemisection, a thermoresponsive and thermoreversible physically cross-linked poly(N-isopropylacrylamide)-poly(ethylene glycol) copolymer...
10.
Trimaille T, Lacroix C, Verrier B
Eur J Pharm Biopharm
. 2019 Jun;
142:232-239.
PMID: 31229673
Subunit vaccines using recombinant antigens appear as the privileged vaccination technology for safety reasons but still require the development of carriers/adjuvants ensuring optimal immunogenicity and efficacy. Micelles from self-assembled amphiphilic...