Thomas R Tolle
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Explore the profile of Thomas R Tolle including associated specialties, affiliations and a list of published articles.
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70
Citations
2798
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Recent Articles
1.
Zebhauser P, Bott F, Gil Avila C, Heitmann H, May E, Tiemann L, et al.
J Pain
. 2025 Jan;
28:104788.
PMID: 39828070
Resting-state electroencephalography (rsEEG) holds promise as a biomarker of chronic pain. However, the impact of centrally acting analgesics like opioids, antiepileptics, and antidepressants on rsEEG remains unclear. This confounds and...
2.
Pickering G, OKeeffe M, Bannister K, Becker S, Cottom S, Cox F, et al.
Eur J Pain
. 2024 Dec;
29(1):e4767.
PMID: 39655849
Background: Pain is the leading cause of disability and reduced quality of life worldwide. Despite the increasing burden for patients and healthcare systems, pain research remains underfunded and under focused....
3.
Sachau J, Kersebaum D, Hullemann P, Adolf D, Kabelitz M, Keller T, et al.
Pain Rep
. 2023 Sep;
8(5):e1098.
PMID: 37772033
Introduction: Patients with neuropathic pain (NP) report a higher impairment of quality of life and sleep than patients with chronic pain without neuropathic characteristics. These include somatosensory peculiarities like allodynia,...
4.
Vollert J, Fardo F, Attal N, Baron R, Bouhassira D, Enax-Krumova E, et al.
Pain
. 2023 Aug;
165(1):216-224.
PMID: 37578447
Paradoxical heat sensation (PHS) is the perception of warmth when the skin is cooled. Paradoxical heat sensation rarely occurs in healthy individuals but more frequently in patients suffering from lesions...
5.
Zieglgansberger W, Brenneisen R, Berthele A, Wotjak C, Bandelow B, Tolle T, et al.
Med Cannabis Cannabinoids
. 2022 Jun;
5(1):61-75.
PMID: 35702403
The development of a high-end cannabinoid-based therapy is the result of intense translational research, aiming to convert recent discoveries in the laboratory into better treatments for patients. Novel compounds and...
6.
Kern K, Vogelmann T, Tolle T
MMW Fortschr Med
. 2022 Apr;
164(Suppl 6):19-27.
PMID: 35449488
Background/objective: In clinical trials, tapentadol prolonged release (PR) showed a more favourable gastrointestinal tolerability profile compared to other strong opioids in the treatment of pain. The present analysis compared tapentadol...
7.
Heitmann H, Gil Avila C, Nickel M, Ta Dinh S, May E, Tiemann L, et al.
Pain
. 2022 Jan;
163(9):e997-e1005.
PMID: 35050961
Chronic pain is a major healthcare issue posing a large burden on individuals and society. Converging lines of evidence indicate that chronic pain is associated with substantial changes of brain...
8.
Fitzcharles M, Petzke F, Tolle T, Hauser W
Drugs
. 2021 Nov;
81(18):2103-2116.
PMID: 34800285
Nociplastic pain is defined as pain due to sensitization of the nervous system, without a sufficient underlying anatomical abnormality to explain the severity of pain. Nociplastic pain may be manifest...
9.
May E, Gil Avila C, Ta Dinh S, Heitmann H, Hohn V, Nickel M, et al.
Pain
. 2021 Apr;
162(12):2894-2908.
PMID: 33863863
Chronic pain is a highly prevalent and severely disabling disease that is associated with substantial changes of brain function. Such changes have mostly been observed when analyzing static measures of...
10.
Freynhagen R, Baron R, Kawaguchi Y, Malik R, Martire D, Parsons B, et al.
Postgrad Med
. 2021 Jan;
133(1):1-9.
PMID: 33423590
Pregabalin is one of the first-line treatments approved for the management of neuropathic pain (NeP). While many patients benefit from treatment with pregabalin, they are often treated with suboptimal doses,...