Thomas R Tolle
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Explore the profile of Thomas R Tolle including associated specialties, affiliations and a list of published articles.
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70
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2798
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Recent Articles
11.
Sachau J, Bruckmueller H, Gierthmuhlen J, Magerl W, May D, Binder A, et al.
Eur J Pain
. 2020 Nov;
25(3):595-611.
PMID: 33171011
Background: The serotonin receptor 2A (HTR2A) has been described as an important facilitation mediator of spinal nociceptive processing leading to central sensitization (CS) in animal models of chronic pain. However,...
12.
Heitmann H, Haller B, Tiemann L, Muhlau M, Berthele A, Tolle T, et al.
Pain
. 2020 Mar;
161(4):787-796.
PMID: 32197038
Pain is frequent in multiple sclerosis (MS) and includes different types, with neuropathic pain (NP) being most closely related to MS pathology. However, prevalence estimates vary largely, and causal relationships...
13.
Ta Dinh S, Nickel M, Tiemann L, May E, Heitmann H, Hohn V, et al.
Pain
. 2019 Jul;
160(12):2751-2765.
PMID: 31356455
Chronic pain is a common and severely disabling disease whose treatment is often unsatisfactory. Insights into the brain mechanisms of chronic pain promise to advance the understanding of the underlying...
14.
Heitmann H, May E, Tiemann L, Schmidt P, Nickel M, Ta Dinh S, et al.
eNeuro
. 2019 Feb;
5(5).
PMID: 30713993
Pain serves vital protective functions, which crucially depend on appropriate motor responses to noxious stimuli. Such responses not only depend on but can themselves shape the perception of pain. In...
15.
May E, Nickel M, Ta Dinh S, Tiemann L, Heitmann H, Voth I, et al.
Hum Brain Mapp
. 2018 Sep;
40(1):293-305.
PMID: 30260531
Chronic pain is a major health care issue characterized by ongoing pain and a variety of sensory, cognitive, and affective abnormalities. The neural basis of chronic pain is still not...
16.
Stankewitz A, Sorg C, von Kalckreuth A, Schulz E, Valet M, Neufang S, et al.
J Neuroimaging
. 2018 Jul;
28(6):621-628.
PMID: 30028554
Background And Purpose: Somatoform pain disorder is characterized by chronic pain and various psychological symptoms including increased attention to mental and physical processes. Given that the medial prefrontal cortex (mPFC)...
17.
Vollert J, Magerl W, Baron R, Binder A, Enax-Krumova E, Geisslinger G, et al.
Pain
. 2018 Mar;
159(6):1090-1102.
PMID: 29494416
As an indirect approach to relate previously identified sensory phenotypes of patients suffering from peripheral neuropathic pain to underlying mechanisms, we used a published sorting algorithm to estimate the prevalence...
18.
Rehm S, GroBkopf M, Kabelitz M, Keller T, Freynhagen R, Tolle T, et al.
Pain Rep
. 2018 Feb;
3(1):e636.
PMID: 29430564
Introduction: Animal experimental evidence suggests that mechanisms of pain generation and response to treatment differ between neuropathic pain in the cephalic and the extracephalic innervation territories. Objectives: The objective of...
19.
Huber S, Priebe J, Baumann K, Plidschun A, Schiessl C, Tolle T
JMIR Rehabil Assist Technol
. 2017 Dec;
4(2):e11.
PMID: 29203460
Background: Even though modern concepts of disease management of unspecific low back pain (LBP) postulate active participation of patients, this strategy is difficult to adapt unless multidisciplinary pain therapy is...
20.
Vollert J, Maier C, Attal N, Bennett D, Bouhassira D, Enax-Krumova E, et al.
Pain
. 2017 Jun;
158(8):1446-1455.
PMID: 28595241
In a recent cluster analysis, it has been shown that patients with peripheral neuropathic pain can be grouped into 3 sensory phenotypes based on quantitative sensory testing profiles, which are...