Thomas Perlot
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Explore the profile of Thomas Perlot including associated specialties, affiliations and a list of published articles.
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19
Citations
1891
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Recent Articles
1.
Cronin S, Tejada M, Song R, Laval K, Cikes D, Ji M, et al.
bioRxiv
. 2023 May;
PMID: 37214906
Infections with defined Herpesviruses, such as Pseudorabies virus (PRV) and Varicella zoster virus (VZV) can cause neuropathic itch, referred to as "mad itch" in multiple species. The underlying mechanisms involved...
2.
Szappanos D, Tschismarov R, Perlot T, Westermayer S, Fischer K, Platanitis E, et al.
PLoS Pathog
. 2018 Nov;
14(11):e1007397.
PMID: 30475900
DExD/H box RNA helicases, such as the RIG-I-like receptors (RLR), are important components of the innate immune system. Here we demonstrate a pivotal and sex-specific role for the heterosomal isoforms...
3.
Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al.
Cell Rep
. 2016 Sep;
16(12):3414.
PMID: 27653700
No abstract available.
4.
Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al.
Cell Rep
. 2016 May;
15(7):1481-1492.
PMID: 27160902
The HECT domain E3 ligase HACE1 has been identified as a tumor suppressor in multiple cancers. Here, we report that HACE1 is a central gatekeeper of TNFR1-induced cell fate. Genetic...
5.
Wirnsberger G, Zwolanek F, Stadlmann J, Tortola L, Liu S, Perlot T, et al.
Nat Genet
. 2014 Aug;
46(9):1028-33.
PMID: 25129145
Neutrophils are key innate immune effector cells that are essential to fighting bacterial and fungal pathogens. Here we report that mice carrying a hematopoietic lineage-specific deletion of Jagn1 (encoding Jagunal...
6.
Rao S, Tortola L, Perlot T, Wirnsberger G, Novatchkova M, Nitsch R, et al.
Nat Commun
. 2014 Jan;
5:3056.
PMID: 24445999
Autophagy is a mechanism by which starving cells can control their energy requirements and metabolic states, thus facilitating the survival of cells in stressful environments, in particular in the pathogenesis...
7.
Perlot T, Penninger J
Microbes Infect
. 2013 Aug;
15(13):866-73.
PMID: 23962453
The renin-angiotensin system (RAS) is a complex network that regulates blood pressure, electrolyte and fluid homeostasis, as well as the function of several organs. Angiotensin-converting enzyme 2 (ACE2) was identified...
8.
Selimyan R, Gerstein R, Ivanova I, Precht P, Subrahmanyam R, Perlot T, et al.
PLoS Biol
. 2013 Feb;
11(1):e1001475.
PMID: 23382652
Multiple epigenetic marks have been proposed to contribute to the regulation of antigen receptor gene assembly via V(D)J recombination. Here we provide a comprehensive view of DNA methylation at the...
9.
Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M, et al.
Nature
. 2012 Jul;
487(7408):477-81.
PMID: 22837003
Malnutrition affects up to one billion people in the world and is a major cause of mortality. In many cases, malnutrition is associated with diarrhoea and intestinal inflammation, further contributing...
10.
Perlot T, Penninger J
J Immunol
. 2012 Jan;
188(3):1201-5.
PMID: 22219325
RANKL-RANK signaling regulates numerous physiologic processes such as bone remodeling, lymph node organogenesis, central thermoregulation, and formation of a lactating mammary gland in pregnancy. Recently, a receptor activator of NF-κB...