Thomas Nolte
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Explore the profile of Thomas Nolte including associated specialties, affiliations and a list of published articles.
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55
Citations
818
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Recent Articles
1.
Nolte T, Halabian R, Israel S, Suzuki Y, Avelar R, Palmer D, et al.
Mol Hum Reprod
. 2025 Jan;
31(1.
PMID: 39786543
Recent advances in embryology have shown that the sister blastomeres of two-cell mouse and human embryos differ reciprocally in potency. An open question is whether the blastomeres became different as...
2.
Arms S, Hempel K, Rau S, Schlichtiger J, Nolte T
Toxicol Pathol
. 2024 Aug;
52(5):295-301.
PMID: 39149788
Degenerative lesions specific to the basal nuclei have not been described as a background finding in Beagle dogs. This report comprises a documentation of seven cases. In the context of...
3.
Vahle J, Dybowski J, Graziano M, Hisada S, Lebron J, Nolte T, et al.
Front Toxicol
. 2024 Jun;
6:1377990.
PMID: 38845817
Industry representatives on the ICH S1B(R1) Expert Working Group (EWG) worked closely with colleagues from the Drug Regulatory Authorities to develop an addendum to the ICH S1B guideline on carcinogenicity...
4.
Lempp C, Arms S, Bertram C, Klopfleisch R, Igl B, Hezler L, et al.
Toxicol Pathol
. 2024 Jun;
52(5):251-257.
PMID: 38829005
Digitalization of pathology workflows has undergone a rapid evolution and has been widely established in the diagnostic field but remains a challenge in the nonclinical safety context due to lack...
5.
Israel S, Seyfarth J, Nolte T, Drexler H, Fuellen G, Boiani M
Mol Hum Reprod
. 2023 Nov;
29(11).
PMID: 37930049
In oocyte biology, the zona pellucida has long been known to operate three extracellular functions downstream of the secretory pathway, namely, encasing the oocytes in ovarian follicles, mediating sperm-oocyte interaction,...
6.
Gierke H, Mouchantat S, Berg S, Grimm M, Hadlich S, Kromrey M, et al.
Pharmaceutics
. 2023 Mar;
15(3).
PMID: 36986751
Spray-dried amorphous solid dispersions of new chemical entities and pH-dependent soluble polymer hydroxypropyl methylcellulose acetate succinate (HPMC-AS) were found to form solid agglomerates in the gastrointestinal tract of rodents after...
7.
Gierke H, Schaefer K, Gerlich L, Willmann A, Bialetzki V, Boeck G, et al.
Pharmaceutics
. 2022 Dec;
14(12).
PMID: 36559103
The formation of pharmacobezoars from suspensions of spray-dried amorphous solid dispersions (SD-ASDs) of new chemical entities (NCEs) and hydroxypropyl methylcellulose acetate succinate (HPMC-AS) represents a non-compound related adverse effect in...
8.
Gierke H, Pfrommer T, Schafer K, Weitschies W, Nolte T
Toxicol Pathol
. 2022 Dec;
50(8):920-929.
PMID: 36541591
Changing the physical state from crystalline to amorphous is an elegant method to increase the bioavailability of poorly soluble new chemical entity (NCE) drug candidates. Subsequently, we report findings from...
9.
Lager A, Spampinato G, Papadopoulos A, Nolte T
Front Robot AI
. 2022 Jul;
9:940811.
PMID: 35845253
[This corrects the article DOI: 10.3389/frobt.2022.816355.].
10.
Lager A, Spampinato G, Papadopoulos A, Nolte T
Front Robot AI
. 2022 May;
9:816355.
PMID: 35572375
Modern industrial robots are increasingly deployed in dynamic environments, where unpredictable events are expected to impact the robot's operation. Under these conditions, runtime task replanning is required to avoid failures...