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Thomas McCarty

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Articles 14
Citations 395
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11.
Bhattacharya P, Grigera F, Rogozin I, McCarty T, Morse 3rd H, Kenter A
Eur J Immunol . 2007 Dec; 38(1):227-39. PMID: 18081040
Activation-induced deaminase (AID) is the master regulator of class switch recombination (CSR) and somatic hypermutation (SHM), but the mechanisms regulating AID function are obscure. The differential pattern of switch plasmid...
12.
Doerre S, Mesires K, Daley K, McCarty T, Knoetig S, Corley R
J Immunol . 2005 Jan; 174(2):983-91. PMID: 15634922
The levels and stability of IkappaBepsilon have been examined in unstimulated and stimulated splenic B cells and compared with that of IkappaBalpha and IkappaBbeta. Primary murine splenic B cells but...
13.
Zhang J, Okumura C, McCarty T, Shin M, Mukhopadhyay P, Hori M, et al.
J Exp Med . 2004 Dec; 200(11):1467-78. PMID: 15583018
Germline mutations in Fas and Fasl induce nonmalignant T cell hyperplasia and systemic autoimmunity and also greatly increase the risk of B cell neoplasms. B lymphomas occurring in Fasl mutant...
14.
Lumsden J, McCarty T, Petiniot L, Shen R, Barlow C, Wynn T, et al.
J Exp Med . 2004 Oct; 200(9):1111-21. PMID: 15504820
Immunoglobulin class switch recombination (Ig CSR) involves DNA double strand breaks (DSBs) at recombining switch regions and repair of these breaks by nonhomologous end-joining. Because the protein kinase ataxia telengiectasia...