Thomas M Zydowsky
Overview
Explore the profile of Thomas M Zydowsky including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
585
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Recent Articles
11.
Villegas G, Calenda G, Ugaonkar S, Zhang S, Kizima L, Mizenina O, et al.
PLoS One
. 2016 Jul;
11(7):e0159332.
PMID: 27428377
Women need multipurpose prevention products (MPTs) that protect against sexually transmitted infections (STIs) and provide contraception. The Population Council has developed a prototype intravaginal ring (IVR) releasing the non-nucleoside reverse...
12.
Villegas G, Calenda G, Zhang S, Mizenina O, Kleinbeck K, Cooney M, et al.
Antimicrob Agents Chemother
. 2016 Jul;
60(9):5459-66.
PMID: 27381393
Our recent phase 1 trial demonstrated that PC-1005 gel containing 50 μM MIV-150, 14 mM zinc acetate dihydrate, and carrageenan (CG) applied daily vaginally for 14 days is safe and...
13.
Jean-Pierre N, Barnable P, Kizima L, Rodriguez A, Seidor S, Cooney M, et al.
Antimicrob Agents Chemother
. 2015 Nov;
60(2):1141-4.
PMID: 26596943
We compared the preclinical safety and efficacy of tenofovir (TFV) 1% gel with that of MZC gel [containing 50 μM MIV-150, 14 mM Zn(O2CCH3)2(H2O)2, and 3% carrageenan] through a series...
14.
Levendosky K, Mizenina O, Martinelli E, Jean-Pierre N, Kizima L, Rodriguez A, et al.
Antimicrob Agents Chemother
. 2015 Sep;
59(12):7290-8.
PMID: 26369967
Extensive preclinical evaluation of griffithsin (GRFT) has identified this lectin to be a promising broad-spectrum microbicide. We set out to explore the antiviral properties of a GRFT and carrageenan (CG)...
15.
Ugaonkar S, Wesenberg A, Wilk J, Seidor S, Mizenina O, Kizima L, et al.
J Control Release
. 2015 Jun;
213:57-68.
PMID: 26091920
Women urgently need a self-initiated, multipurpose prevention technology (MPT) that simultaneously reduces their risk of acquiring HIV-1, HSV-2, and HPV (latter two associated with increased risk of HIV-1 acquisition) and...
16.
Barnable P, Calenda G, Bonnaire T, Menon R, Levendosky K, Gettie A, et al.
Antimicrob Agents Chemother
. 2015 Apr;
59(7):3829-37.
PMID: 25870063
The transmission of both cell-free and cell-associated immunodeficiency viruses has been demonstrated directly in multiple animal species and possibly occurs in humans, as suggested by genotyping of the infecting human...
17.
Fernandez-Romero J, Teleshova N, Zydowsky T, Robbiani M
Adv Drug Deliv Rev
. 2014 Dec;
92:27-38.
PMID: 25543007
Sexually transmitted infections like HIV, HPV, and HSV-2, as well as unplanned pregnancy, take a huge toll on women worldwide. Woman-initiated multipurpose prevention technologies that contain antiviral/antibacterial drugs (microbicides) and...
18.
Kenney J, Derby N, Aravantinou M, Kleinbeck K, Frank I, Gettie A, et al.
AIDS Res Hum Retroviruses
. 2014 Oct;
30(11):1117-24.
PMID: 25354024
Epidemiological studies suggest that prevalent herpes simplex virus type 2 (HSV-2) infection increases the risk of HIV acquisition, underscoring the need to develop coinfection models to evaluate promising prevention strategies....
19.
Barnable P, Calenda G, Ouattara L, Gettie A, Blanchard J, Jean-Pierre N, et al.
PLoS One
. 2014 Sep;
9(9):e108109.
PMID: 25259616
To extend our observations that single or repeated application of a gel containing the NNRTI MIV-150 (M) and zinc acetate dihydrate (ZA) in carrageenan (CG) (MZC) inhibits vaginal transmission of...
20.
Kizima L, Rodriguez A, Kenney J, Derby N, Mizenina O, Menon R, et al.
PLoS One
. 2014 Apr;
9(4):e94547.
PMID: 24740100
Prevalent infection with human herpes simplex 2 (HSV-2) or human papillomavirus (HPV) is associated with increased human immunodeficiency virus (HIV) acquisition. Microbicides that target HIV as well as these sexually...