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Thomas M Valentin

Explore the profile of Thomas M Valentin including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 489
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Recent Articles
1.
Leggett S, Patel M, Valentin T, Gamboa L, Khoo A, Williams E, et al.
Proc Natl Acad Sci U S A . 2020 Mar; 117(11):5655-5663. PMID: 32123100
Epithelial tissues mechanically deform the surrounding extracellular matrix during embryonic development, wound repair, and tumor invasion. Ex vivo measurements of such multicellular tractions within three-dimensional (3D) biomaterials could elucidate collective...
2.
Khoo A, Valentin T, Leggett S, Bhaskar D, Bye E, Benmelech S, et al.
ACS Biomater Sci Eng . 2019 Sep; 5(9):4341-4354. PMID: 31517039
Invading cancer cells adapt their migration phenotype in response to mechanical and biochemical cues from the extracellular matrix. For instance, mesenchymal migration is associated with strong cell-matrix adhesions and an...
3.
Valentin T, Leggett S, Chen P, Sodhi J, Stephens L, McClintock H, et al.
Lab Chip . 2017 Sep; 17(20):3474-3488. PMID: 28906525
3D printed biomaterials with spatial and temporal functionality could enable interfacial manipulation of fluid flows and motile cells. However, such dynamic biomaterials are challenging to implement since they must be...
4.
Chen P, Liu M, Valentin T, Wang Z, Spitz Steinberg R, Sodhi J, et al.
ACS Nano . 2016 Dec; 10(12):10869-10879. PMID: 28024363
Confined assembly in the intersheet gallery spaces of two-dimensional (2D) materials is an emerging templating route for creation of ultrathin material architectures. Here, we demonstrate a general synthetic route for...
5.
Wang Z, von dem Bussche A, Qiu Y, Valentin T, Gion K, Kane A, et al.
Environ Sci Technol . 2016 Jun; 50(13):7208-17. PMID: 27267956
Material stability and dissolution in aqueous media are key issues to address in the development of a new nanomaterial intended for technological application. Dissolution phenomena affect biological and environmental persistence;...
6.
Chen P, Sodhi J, Qiu Y, Valentin T, Spitz Steinberg R, Wang Z, et al.
Adv Mater . 2016 Mar; 28(18):3564-71. PMID: 26996525
Multigenerational graphene oxide architectures can be programmed by specific sequences of mechanical deformations. Each new deformation results in a progressively larger set of features decorated by smaller preexisting patterns, indicating...
7.
Leslie D, Waterhouse A, Berthet J, Valentin T, Watters A, Jain A, et al.
Nat Biotechnol . 2014 Oct; 32(11):1134-40. PMID: 25306244
Thrombosis and biofouling of extracorporeal circuits and indwelling medical devices cause significant morbidity and mortality worldwide. We apply a bioinspired, omniphobic coating to tubing and catheters and show that it...
8.
Kang J, Super M, Yung C, Cooper R, Domansky K, Graveline A, et al.
Nat Med . 2014 Sep; 20(10):1211-6. PMID: 25216635
Here we describe a blood-cleansing device for sepsis therapy inspired by the spleen, which can continuously remove pathogens and toxins from blood without first identifying the infectious agent. Blood flowing...
9.
Tang-Schomer M, White J, Tien L, Schmitt L, Valentin T, Graziano D, et al.
Proc Natl Acad Sci U S A . 2014 Aug; 111(38):13811-6. PMID: 25114234
The brain remains one of the most important but least understood tissues in our body, in part because of its complexity as well as the limitations associated with in vivo...