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Thomas M Bartlett

Explore the profile of Thomas M Bartlett including associated specialties, affiliations and a list of published articles. Areas
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Citations 87
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Recent Articles
1.
Kuru E, Rittichier J, de Puig H, Flores A, Rout S, Han I, et al.
Nat Commun . 2024 Sep; 15(1):7531. PMID: 39237489
Binding-activated optical sensors are powerful tools for imaging, diagnostics, and biomolecular sensing. However, biosensor discovery is slow and requires tedious steps in rational design, screening, and characterization. Here we report...
2.
Bartlett T, Sisley T, Mychack A, Walker S, Baker R, Rudner D, et al.
Nat Microbiol . 2024 Mar; 9(3):801-813. PMID: 38443581
Staphylococcus aureus is a Gram-positive pathogen responsible for antibiotic-resistant infections. To identify vulnerabilities in cell envelope biogenesis that may overcome resistance, we enriched for S. aureus transposon mutants with defects...
3.
Bartlett T, Sisley T, Mychack A, Walker S, Baker R, Rudner D, et al.
bioRxiv . 2023 May; PMID: 37162900
is a gram-positive pathogen responsible for life-threatening infections that are difficult to treat due to antibiotic resistance. The identification of new vulnerabilities in essential processes like cell envelope biogenesis represents...
4.
Martin N, Blackman E, Bratton B, Chase K, Bartlett T, Gitai Z
Nat Microbiol . 2021 Jun; 6(7):910-920. PMID: 34183815
Bacterial species have diverse cell shapes that enable motility, colonization and virulence. The cell wall defines bacterial shape and is primarily built by two cytoskeleton-guided synthesis machines, the elongasome and...
5.
Wucher B, Bartlett T, Hoyos M, Papenfort K, Persat A, Nadell C
Proc Natl Acad Sci U S A . 2019 Jun; 116(28):14216-14221. PMID: 31239347
Collective behavior in spatially structured groups, or biofilms, is the norm among microbes in their natural environments. Though biofilm formation has been studied for decades, tracing the mechanistic and ecological...
6.
Bartlett T, Bratton B, Duvshani A, Miguel A, Sheng Y, Martin N, et al.
Cell . 2017 Jan; 168(1-2):172-185.e15. PMID: 28086090
Pathogenic Vibrio cholerae remains a major human health concern. V. cholerae has a characteristic curved rod morphology, with a longer outer face and a shorter inner face. The mechanism and...