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Thomas Leitner

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Articles 113
Citations 2687
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Recent Articles
1.
Lapp Z, Yoon H, Foley B, Leitner T
Bioinform Adv . 2025 Feb; 5(1):vbaf025. PMID: 39981109
Motivation: The detection of APOBEC3F- and APOBEC3G-induced mutations in virus sequences is useful for identifying hypermutated sequences. These sequences are not representative of viral evolution and can therefore alter the...
2.
Lapp Z, Yoon H, Foley B, Leitner T
bioRxiv . 2024 Nov; PMID: 39553937
The detection of APOBEC3F- and APOBEC3G-induced mutations in virus sequences is useful for identifying hypermutated sequences. These sequences are not representative of viral evolution and can therefore alter the results...
3.
Lundgren E, Locke M, Romero-Severson E, Dimitrijevic M, Axelsson M, Andersson E, et al.
Euro Surveill . 2024 Oct; 29(42). PMID: 39421951
BackgroundSweden reached the UNAIDS 90-90-90 target in 2015. It is important to reassess the HIV epidemiological situation due to ever-changing migration patterns, the roll-out of PrEP and the impact of...
4.
Mbisa J, Lapp Z, Bibby D, Phillips L, Manso C, Packer S, et al.
J Infect Dis . 2024 May; 230(6):e1254-e1262. PMID: 38717937
Background: Hepatitis C virus (HCV) has high genetic diversity and is classified into 8 genotypes and >90 subtypes, with some endemic to specific world regions. This could compromise direct-acting antiviral...
5.
Lin Q, Goldberg E, Leitner T, Molina-Paris C, King A, Romero-Severson E
Mol Biol Evol . 2024 Apr; 41(6). PMID: 38648521
Reassortment is an evolutionary process common in viruses with segmented genomes. These viruses can swap whole genomic segments during cellular co-infection, giving rise to novel progeny formed from the mixture...
6.
Belluccini G, Lin Q, Williams B, Lou Y, Vatansever Z, Lopez-Garcia M, et al.
ArXiv . 2024 Apr; PMID: 38562445
With a single circulating vector-borne virus, the basic reproduction number incorporates contributions from tick-to-tick (co-feeding), tick-to-host and host-to-tick transmission routes. With two different circulating vector-borne viral strains, resident and invasive,...
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Gruber G, Schweighofer B, Berger M, Leitner T, Kloesch G, Wegleiter H
Sensors (Basel) . 2024 Mar; 24(5). PMID: 38475018
Eddy current displacement sensors (ECDSs) are widely used for the noncontact position measurement of small displacements (lift-offs). Challenges arise with larger displacements as the sensitivity of the ECDSs decreases. This...
9.
Goldberg E, Lundgren E, Romero-Severson E, Leitner T
Mol Biol Evol . 2023 Dec; 41(1). PMID: 38149995
When the time of an HIV transmission event is unknown, methods to identify it from virus genetic data can reveal the circumstances that enable transmission. We developed a single-parameter Markov...
10.
Kupperman M, Ke R, Leitner T
bioRxiv . 2023 Dec; PMID: 38076930
Robust sampling methods are foundational to inferences using phylogenies. Yet the impact of using contact tracing, a type of non-uniform sampling used in public health applications such as infectious disease...