Thomas L Andresen
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Explore the profile of Thomas L Andresen including associated specialties, affiliations and a list of published articles.
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160
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2363
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Recent Articles
11.
Lund P, Kristensen K, Larsen N, Knuhtsen A, Hansen M, Hjorringgaard C, et al.
J Colloid Interface Sci
. 2024 May;
669:198-210.
PMID: 38713958
A widespread strategy to increase the transport of therapeutic peptides across cellular membranes has been to attach lipid moieties to the peptide backbone (lipidation) to enhance their intrinsic membrane interaction....
12.
Munter R, Bak M, Thomsen M, Parhamifar L, Stensballe A, Simonsen J, et al.
Int J Pharm
. 2024 Apr;
657:124129.
PMID: 38621615
Cationic liposomes specifically target monocytes in blood, rendering them promising drug-delivery tools for cancer immunotherapy, vaccines, and therapies for monocytic leukaemia. The mechanism behind this monocyte targeting ability is, however,...
13.
Wiinberg M, Andresen T, Haedersdal M, Olesen U
Lasers Surg Med
. 2024 Feb;
56(3):270-278.
PMID: 38409449
Objectives: Ablative fractional laser (AFL) treatment is a well-established method for reducing signs of skin photoaging. However, the biological mechanisms underlying AFL-induced healing responses and skin rejuvenation remain largely unknown....
14.
Weller S, Li X, Petersen L, Kempen P, Clergeaud G, Andresen T
Int Immunopharmacol
. 2024 Feb;
129:111643.
PMID: 38340420
Particle-based systems have become a state-of-the-art method for in vitro expanding cytotoxic T cells by tailoring their surface with activating molecules. However, commonly used methods utilize facile carbodiimide chemistry leading...
15.
Olesen U, Pedersen K, Togsverd-Bo K, Biskup E, Nielsen A, Jackerott M, et al.
Lasers Surg Med
. 2024 Feb;
56(3):239-248.
PMID: 38311811
Background: Systemically delivered hedgehog inhibitors including vismodegib and sonidegib are widely used to treat basal cell carcinomas (BCCs). Ablative fractional laser (AFL)-assisted topical delivery of vismodegib has been demonstrated in...
16.
Li X, Weller S, Clergeaud G, Andresen T
Biotechnol J
. 2024 Jan;
19(1):e2300339.
PMID: 38178719
Cell-mediated drug delivery by conjugating nanomedicine to the surface of living cells is a promising strategy for enhancing the efficacy of both drug delivery and cell therapy. It exploits the...
17.
Norgard M, Lund P, Kalisi N, Andresen T, Larsen J, Vogel S, et al.
FASEB Bioadv
. 2023 Sep;
5(9):355-366.
PMID: 37674540
Extracellular vesicle (EV) secretion rate is stimulated by hypoxia that causes increased reactive oxygen species (ROS) production by the mitochondrial electron transport chain (ETC) and hypoxia-induced factor (HIF)-1 signaling; however,...
18.
Munter R, Christensen E, Andresen T, Larsen J
Mol Ther Methods Clin Dev
. 2023 May;
29:450-459.
PMID: 37251983
Following the recent approval of both siRNA- and mRNA-based therapeutics, nucleic acid therapies are considered a game changer in medicine. Their envisioned widespread use for many therapeutic applications with an...
19.
Munter R, Sorensen E, Hasselbalch R, Christensen E, Nielsen S, Garred P, et al.
Mol Pharm
. 2023 Mar;
20(7):3356-3366.
PMID: 36952227
Despite the success of mRNA-based vaccines against infectious diseases (including COVID-19), safety concerns have been raised relating to the lipid nanoparticles (LNPs) used to deliver the mRNA cargo. Antibodies against...
20.
Simon M, Jorgensen J, Norregaard K, Henriksen J, Clergeaud G, Andresen T, et al.
Int J Nanomedicine
. 2023 Feb;
18:829-841.
PMID: 36824412
Introduction: Traditional cancer treatments, such as chemotherapy, are often incapable of achieving complete responses as standalone therapies. Hence, current treatment strategies typically rely on a combination of several approaches. Nanoparticle-based...