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Thomas Korn

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Articles 164
Citations 17135
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Recent Articles
1.
Afzali A, Ulianov O, Eckardt L, Stas I, Seeholzer L, Steiger K, et al.
Acta Neuropathol Commun . 2025 Feb; 13(1):27. PMID: 39934927
Neuromyelitis optica spectrum disorder (NMOSD) is a paradigmatic autoimmune disease of the central nervous system (CNS), in which the water channel protein Aquaporin-4 (AQP4) is targeted by a self-reactive immune...
2.
Diehl C, Soberon V, Baygun S, Chu Y, Mandelbaum J, Kraus L, et al.
Immunity . 2024 Dec; 58(1):124-142.e15. PMID: 39729992
B cell immunity carries the inherent risk of deviating into autoimmunity and malignancy, which are both strongly associated with genetic variants or alterations that increase immune signaling. Here, we investigated...
3.
Afzali A, Vosko M, Reinhardt N, Zinevych I, Gmeiner V, Korn T, et al.
Eur J Neurol . 2024 Nov; 32(1):e16539. PMID: 39562307
Background And Purpose: The purpose was to explore the prognostic utility of neurofilament light chain (NfL) in patients with immune-mediated polyradiculoneuropathies (IMPs). Methods: This retrospective monocentric study analysed serum and...
4.
Korn T
Immunity . 2024 Oct; 57(10):2258-2260. PMID: 39383840
Understanding the nature of human autoantigen-specific CD4 T cells is limited by the difficulty of characterizing these cells ex vivo. In this issue of Immunity, Saggau et al. use ARTE...
5.
Kavaka V, Mutschler L, de la Rosa Del Val C, Eglseer K, Gomez Martinez A, Flierl-Hecht A, et al.
Sci Immunol . 2024 Sep; 9(99):eadj8094. PMID: 39331727
Multiple sclerosis (MS) is an inflammatory neurological disease of the central nervous system with a subclinical phase preceding frank neuroinflammation. CD8 T cells are abundant within MS lesions, but their...
6.
Wicklein R, Kreitner L, Wild A, Aly L, Rueckert D, Hemmer B, et al.
Mult Scler . 2024 May; 30(7):812-819. PMID: 38751230
Background: Alterations of the superficial retinal vasculature are commonly observed in multiple sclerosis (MS) and can be visualized through optical coherence tomography angiography (OCTA). Objectives: This study aimed to examine...
7.
Wolf E, Wicklein R, Aly L, Schmaderer C, Afzali A, Mardin C, et al.
J Neurol . 2024 May; 271(7):4610-4619. PMID: 38743089
Background: While retinal vessel changes are evident in the eyes of patients with relapsing-remitting multiple sclerosis (RRMS), changes in the vasculature of possible MS mimics such as primary Sjögren's syndrome...
8.
Chang Y, Bach L, Hasiuk M, Wen L, Elmzzahi T, Tsui C, et al.
Sci Immunol . 2024 Mar; 9(93):eadd4818. PMID: 38427718
T follicular helper (T) cells are essential for effective antibody responses, but deciphering the intrinsic wiring of mouse T cells has long been hampered by the lack of a reliable...
9.
Baeten P, Hamad I, Hoeks C, Hiltensperger M, Van Wijmeersch B, Popescu V, et al.
JCI Insight . 2024 Feb; 9(7). PMID: 38386413
In autoimmunity, FOXP3+ Tregs skew toward a proinflammatory, nonsuppressive phenotype and are, therefore, unable to control the exaggerated autoimmune response. This largely affects the success of autologous Treg therapy, which...
10.
Afzali A, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, et al.
Nature . 2024 Feb; 627(8003):407-415. PMID: 38383779
Neuromyelitis optica is a paradigmatic autoimmune disease of the central nervous system, in which the water-channel protein AQP4 is the target antigen. The immunopathology in neuromyelitis optica is largely driven...