Thomas J Wiggins
Overview
Explore the profile of Thomas J Wiggins including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
23
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0
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Recent Articles
1.
Mulholland C, Wiggins T, Cui J, Vilcheze C, Rajagopalan S, Shultis M, et al.
Nat Microbiol
. 2024 May;
9(6):1607-1618.
PMID: 38740932
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of Mycobacterium tuberculosis. In vitro culturing rapidly selects for spontaneous PDIM-negative mutants that have attenuated virulence and increased cell wall permeability, thus...
2.
Mulholland C, Wiggins T, Cui J, Vilcheze C, Rajagopalan S, Shultis M, et al.
bioRxiv
. 2023 Oct;
PMID: 37905120
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of . culturing rapidly selects for spontaneous mutations that cause PDIM loss leading to virulence attenuation and increased cell wall permeability. We...
3.
Hasenoehrl E, Wiggins T, Berney M
Front Cell Infect Microbiol
. 2021 Jan;
10:611683.
PMID: 33505923
Development of novel anti-tuberculosis combination regimens that increase efficacy and reduce treatment timelines will improve patient compliance, limit side-effects, reduce costs, and enhance cure rates. Such advancements would significantly improve...