Saranathan Rajagopalan
Overview
Explore the profile of Saranathan Rajagopalan including associated specialties, affiliations and a list of published articles.
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8
Citations
18
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Recent Articles
1.
Thwe P, Rajagopalan S, Orner E
Clin Lab Med
. 2025 Feb;
45(1):87-99.
PMID: 39892940
While Mycobacterium species cause various infections, extrapulmonary tuberculosis (EPTB) and nontuberculous mycobacterial (NTM) infections were overlooked in the past. However, the incidence rates of these infections have increased over time....
2.
Rajagopalan S, Rourke A, Asare E, Kohlerschmidt D, Das L, Ngema S, et al.
J Infect Dis
. 2024 Oct;
PMID: 39412357
Background: Drug-resistant tuberculosis is a growing public health threat, and early characterization of the resistance phenotype is essential for guiding treatment and mitigating the high mortality associated with the disease....
3.
Vilcheze C, Rajagopalan S, Jacobs W
bioRxiv
. 2024 Sep;
PMID: 39282434
Tuberculosis, caused by ( ), remains a leading infectious cause of mortality worldwide despite widespread use of the BCG vaccine and the availability of sterilizing pharmacopoeia. Recent research indicates that...
4.
Xander C, Rajagopalan S, Jacobs Jr W, Braunstein M
Infect Immun
. 2024 Jun;
92(7):e0021724.
PMID: 38884474
() is an intracellular pathogen that survives and grows in macrophages. A mechanism used by to achieve intracellular survival is to secrete effector molecules that arrest the normal process of...
5.
Mulholland C, Wiggins T, Cui J, Vilcheze C, Rajagopalan S, Shultis M, et al.
Nat Microbiol
. 2024 May;
9(6):1607-1618.
PMID: 38740932
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of Mycobacterium tuberculosis. In vitro culturing rapidly selects for spontaneous PDIM-negative mutants that have attenuated virulence and increased cell wall permeability, thus...
6.
Mulholland C, Wiggins T, Cui J, Vilcheze C, Rajagopalan S, Shultis M, et al.
bioRxiv
. 2023 Oct;
PMID: 37905120
Phthiocerol dimycocerosate (PDIM) is an essential virulence lipid of . culturing rapidly selects for spontaneous mutations that cause PDIM loss leading to virulence attenuation and increased cell wall permeability. We...
7.
Feng M, Namanja-Magliano H, Rajagopalan S, Mishra T, Ducati R, Hirsch B, et al.
ACS Infect Dis
. 2023 Mar;
9(4):966-978.
PMID: 36920074
is found in the gut lining of more than half of the world's population, causes gastric ulcers, and contributes to stomach cancers. Menaquinone synthesis in relies on the rare futalosine...
8.
Kaugars K, Dardick J, de Oliveira A, Weiss K, Lukose R, Kim J, et al.
Proc Natl Acad Sci U S A
. 2021 Aug;
118(34).
PMID: 34417304
Despite widespread yearly vaccination, influenza leads to significant morbidity and mortality across the globe. To make a more broadly protective influenza vaccine, it may be necessary to elicit antibodies that...
9.
Ramakrishnan K, Rajagopalan S, Nair S, Kenchappa P, Chandrakesan S
Indian J Pathol Microbiol
. 2014 Oct;
57(4):579-82.
PMID: 25308010
Introduction: Pseudomonas aeruginosa is a potent opportunistic nosocomial human pathogen among Gram-negative bacteria causing various life-threatening infections in patients from Intensive Care Units. This bacterium has become resistant to almost...