Thomas J Van Blarcom
Overview
Explore the profile of Thomas J Van Blarcom including associated specialties, affiliations and a list of published articles.
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5
Citations
107
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Recent Articles
1.
Lin R, Sutton J, Bentley T, Vargas-Inchaustegui D, Nguyen D, Cheng H, et al.
Sci Adv
. 2023 Aug;
9(31):eadg8694.
PMID: 37540748
The magnitude of CAR T cell expansion has been associated with clinical efficacy. Although cytokines can augment CAR T cell proliferation, systemically administered cytokines can result in toxicities. To gain...
2.
Lin R, Nager A, Park S, Sutton J, Lay C, Melton Z, et al.
Cancer Immunol Res
. 2022 Jul;
10(9):1069-1083.
PMID: 35881865
Although cytokine support can enhance CAR T-cell function, coadministering cytokines or engineering CAR T cells to secrete cytokines can result in toxicities. To mitigate these safety risks, we engineered iTurboCAR...
3.
Park S, Pascua E, Lindquist K, Kimberlin C, Deng X, Mak Y, et al.
Nat Commun
. 2021 Jan;
12(1):710.
PMID: 33514714
Antibody-based therapeutics have experienced a rapid growth in recent years and are now utilized in various modalities spanning from conventional antibodies, antibody-drug conjugates, bispecific antibodies to chimeric antigen receptor (CAR)...
4.
Panowski S, Kuo T, Zhang Y, Chen A, Geng T, Aschenbrenner L, et al.
Mol Cancer Ther
. 2019 Aug;
18(11):2008-2020.
PMID: 31434693
The restricted expression pattern of B-cell maturation antigen (BCMA) makes it an ideal tumor-associated antigen (TAA) for the treatment of myeloma. BCMA has been targeted by both CD3 bispecific antibody...
5.
Abdiche Y, Miles A, Eckman J, Foletti D, Van Blarcom T, Yeung Y, et al.
PLoS One
. 2014 Mar;
9(3):e92451.
PMID: 24651868
Here, we demonstrate how array-based label-free biosensors can be applied to the multiplexed interaction analysis of large panels of analyte/ligand pairs, such as the epitope binning of monoclonal antibodies (mAbs)....