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Thomas G Oertner

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Articles 66
Citations 3412
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Recent Articles
1.
Ahmed A, Alegret N, Almeida B, Alvarez-Puebla R, Andrews A, Ballerini L, et al.
ACS Nano . 2025 Mar; PMID: 40063703
Interfacing artificial devices with the human brain is the central goal of neurotechnology. Yet, our imaginations are often limited by currently available paradigms and technologies. Suggestions for brain-machine interfaces have...
2.
Bitar L, Puig B, Oertner T, Denes A, Magnus T
Transl Stroke Res . 2024 Aug; PMID: 39103660
The direct interplay between the immune and nervous systems is now well established. Within the brain, these interactions take place between neurons and resident glial cells, i.e., microglia and astrocytes,...
3.
Veprek N, Cooper M, Laprell L, Yang E, Folkerts S, Bao R, et al.
J Am Chem Soc . 2024 Mar; 146(13):8895-8903. PMID: 38511265
Actin is one of the most abundant proteins in eukaryotic cells and is a key component of the cytoskeleton. A range of small molecules has emerged that interfere with actin...
4.
Veprek N, Cooper M, Laprell L, Yang E, Folkerts S, Bao R, et al.
bioRxiv . 2023 Jul; PMID: 37502978
Actin is one of the most abundant proteins in eukaryotic cells and a key component of the cytoskeleton. A range of small molecules have emerged that interfere with actin dynamics...
5.
Lamothe-Molina P, Franzelin A, Beck L, Li D, Auksutat L, Fieblinger T, et al.
Nat Commun . 2022 Oct; 13(1):6376. PMID: 36289226
Mice display signs of fear when neurons that express cFos during fear conditioning are artificially reactivated. This finding gave rise to the notion that cFos marks neurons that encode specific...
6.
Durst C, Wiegert J, Schulze C, Helassa N, Torok K, Oertner T
Nat Commun . 2022 Oct; 13(1):6126. PMID: 36253353
Information processing in the brain is controlled by quantal release of neurotransmitters, a tightly regulated process. From ultrastructural analysis, it is known that presynaptic boutons along single axons differ in...
7.
Fieblinger T, Perez-Alvarez A, Lamothe-Molina P, Gee C, Oertner T
EMBO Rep . 2022 Jun; 23(8):e54361. PMID: 35735260
The striatum is a subcortical brain region responsible for the initiation and termination of voluntary movements. Striatal spiny projection neurons receive major excitatory synaptic input from neocortex and thalamus, and...
8.
Fearey B, Binkle L, Mensching D, Schulze C, Lohr C, Friese M, et al.
Sci Rep . 2022 Apr; 12(1):6000. PMID: 35397639
The transient receptor potential melastatin 4 (TRPM4) channel contributes to disease severity in the murine experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis and to neuronal cell death in models...
9.
Pulin M, Stockhausen K, Masseck O, Kubitschke M, Busse B, Wiegert J, et al.
Biomed Opt Express . 2022 Mar; 13(2):777-790. PMID: 35284188
Fluorescent proteins are excited by light that is polarized parallel to the dipole axis of the chromophore. In two-photon microscopy, polarized light is used for excitation. Here we reveal surprisingly...
10.
Anisimova M, van Bommel B, Wang R, Mikhaylova M, Wiegert J, Oertner T, et al.
Cereb Cortex . 2022 Feb; 33(1):23-34. PMID: 35203089
Spike-timing-dependent plasticity (STDP) is a candidate mechanism for information storage in the brain, but the whole-cell recordings required for the experimental induction of STDP are typically limited to 1 h....