Thomas G Gant
Overview
Explore the profile of Thomas G Gant including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
145
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Recent Articles
1.
Gant T
J Med Chem
. 2013 Dec;
57(9):3595-611.
PMID: 24294889
Deuterium, the stable isotope of hydrogen, is known to medicinal chemists for its utility in mechanistic, spectroscopic, and tracer studies. In fact, well-known applications utilizing deuterium exist within every subdiscipline...
2.
Lippa B, Morris J, Corbett M, Kwan T, Noe M, Snow S, et al.
Bioorg Med Chem Lett
. 2006 Apr;
16(13):3444-8.
PMID: 16632359
The design, synthesis, and biological evaluation of potent inhibitors of the TrkA kinase is presented. A homology model is created to aid in the enhancement of potency and selectivity of...
3.
Hong S, Lubben T, Dolliver C, Petrolonis A, Roy R, Li Z, et al.
Bioorg Chem
. 2005 Jan;
33(1):34-44.
PMID: 15668181
Mitogen-activated protein kinase phosphatase-4 (MKP-4) is a dual specificity phosphatase, which acts as a negative regulator of insulin-stimulated pathways. Here, we describe expression, purification, and biochemical characterization of MKP-4. We...