Thomas G Brooks
Overview
Explore the profile of Thomas G Brooks including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
107
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Naik A, Forrest K, Paul O, Issah Y, Valekunja U, Tang S, et al.
JCI Insight
. 2023 Jul;
8(16).
PMID: 37463053
Optimal lung repair and regeneration are essential for recovery from viral infections, including influenza A virus (IAV). We have previously demonstrated that acute inflammation and mortality induced by IAV is...
12.
Meng H, Sengupta A, Ricciotti E, Mrcela A, Mathew D, Mazaleuskaya L, et al.
bioRxiv
. 2023 Jul;
PMID: 37398323
Lipids may influence cellular penetrance by pathogens and the immune response that they evoke. Here we find a broad based lipidomic storm driven predominantly by secretory (s) phospholipase A (sPLA...
13.
Meta-analysis of Diurnal Transcriptomics in Mouse Liver Reveals Low Repeatability of Rhythm Analyses
Brooks T, Manjrekar A, Mrcela A, Grant G
J Biol Rhythms
. 2023 Jun;
38(6):556-570.
PMID: 37382061
To assess the consistency of biological rhythms across studies, 57 public mouse liver tissue timeseries totaling 1096 RNA-seq samples were obtained and analyzed. Only the control groups of each study...
14.
Jamal N, Brooks T, Cohen J, Townsend R, de Sosa G, Shah V, et al.
medRxiv
. 2023 May;
PMID: 37205602
Background: Chronic kidney disease (CKD) represents a significant global burden. Hypertension is a modifiable risk factor for rapid progression of CKD. Methods: We extend the risk stratification by introducing the...
15.
Anderson S, Meng H, Brooks T, Tang S, Lordan R, Sengupta A, et al.
Sci Transl Med
. 2023 May;
15(696):eabo2022.
PMID: 37196066
Longitudinal studies associate shiftwork with cardiometabolic disorders but do not establish causation or elucidate mechanisms of disease. We developed a mouse model based on shiftwork schedules to study circadian misalignment...
16.
Brooks T, Lahens N, Mrcela A, Sarantopoulou D, Nayak S, Naik A, et al.
bioRxiv
. 2023 May;
PMID: 37162982
Simulation of RNA-seq reads is critical in the assessment, comparison, benchmarking, and development of bioinformatics tools. Yet the field of RNA-seq simulators has progressed little in the last decade. To...
17.
Brooks T, Mrcela A, Lahens N, Paschos G, Grosser T, Skarke C, et al.
J Biol Rhythms
. 2021 Nov;
37(1):43-52.
PMID: 34724846
Circadian omics analyses present investigators with large amounts of data to consider and many choices for methods of analysis. Visualization is crucial as rhythmicity can take many forms and -values...
18.
Lahens N, Brooks T, Sarantopoulou D, Nayak S, Lawrence C, Mrcela A, et al.
BMC Genomics
. 2021 Sep;
22(1):692.
PMID: 34563123
Background: The accurate interpretation of RNA-Seq data presents a moving target as scientists continue to introduce new experimental techniques and analysis algorithms. Simulated datasets are an invaluable tool to accurately...
19.
Sarantopoulou D, Brooks T, Nayak S, Mrcela A, Lahens N, Grant G
BMC Bioinformatics
. 2021 May;
22(1):266.
PMID: 34034652
Background: Full-length isoform quantification from RNA-Seq is a key goal in transcriptomics analyses and has been an area of active development since the beginning. The fundamental difficulty stems from the...
20.
Issah Y, Naik A, Tang S, Forrest K, Brooks T, Lahens N, et al.
Elife
. 2021 Mar;
10.
PMID: 33650487
Adverse early-life exposures have a lasting negative impact on health. Neonatal hyperoxia that is a risk factor for bronchopulmonary dysplasia confers susceptibility to influenza A virus (IAV) infection later in...