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Thomas F Newton

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Articles 77
Citations 1294
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Recent Articles
1.
Patel M, Nielsen D, Kosten T, De La Garza 2nd R, Newton T, Verrico C
Am J Addict . 2018 Aug; 27(7):567-573. PMID: 30126012
Background And Objectives: The endogenous cannabinoid anandamide (AEA), an agonist at type-1 cannabinoid (CB1) receptors, is metabolized by fatty acid amide hydrolase (FAAH). The common variant rs324420 C->A within the...
2.
Yoon J, Weaver M, De La Garza 2nd R, Suchting R, Nerumalla C, Omar Y, et al.
Am J Addict . 2018 Jul; PMID: 30024076
Background And Objectives: Delay discounting is associated with numerous clinically significant aspects of substance use disorders (SUDs). Recent studies have demonstrated that different models for assessing discounting may result in...
3.
Yammine L, Kosten T, Cinciripini P, Green C, Meininger J, Minnix J, et al.
Medicine (Baltimore) . 2018 Feb; 97(2):e9567. PMID: 29480848
Background: Cigarette smoking is the greatest preventable cause of morbidity and premature mortality in the United States. Approved pharmacological treatments for smoking cessation are marginally effective, underscoring the need for...
4.
Yoon J, De La Garza 2nd R, Newton T, Suchting R, Weaver M, Brown G, et al.
Psychol Rec . 2017 Oct; 67(3):355-363. PMID: 28970640
Delay discounting describes how a reward loses value as a function of increasing delay to its receipt and has been reliably associated with a variety of vulnerable populations including those...
5.
Mahoney 3rd J, Kalechstein A, Newton T, De La Garza 2nd R
J Psychopharmacol . 2017 Jul; 31(8):989-995. PMID: 28695777
It is well-documented in the literature that cocaine use is associated with neurocognitive impairment. The manner in which patterns of cocaine use, such as years of use, recent use over...
6.
Mathai D, Holst M, Rodgman C, Haile C, Keller J, Hussain M, et al.
J Neuropsychiatry Clin Neurosci . 2017 Jun; 30(1):66-76. PMID: 28641496
The cannabinoid-1 receptor (CB1R) agonist Δ9-tetrahydrocannabinol (THC), the main psychoactive constituent of cannabis, adversely effects working memory performance in humans. The α2A-adrenoceptor (AR) agonist guanfacine improves working memory performance in...
7.
Patriquin M, Hamon S, Harding M, Nielsen E, Newton T, De La Garza 2nd R, et al.
Psychiatr Genet . 2017 Jun; 27(5):178-186. PMID: 28590957
Objective: This study investigated variants of tryptophan hydroxylase (TPH)1, TPH2, and SLC6A4 in the moderation of the subjective effects of cocaine. Methods: Non-treatment-seeking cocaine-dependent individuals (N=66) were intravenously administered saline...
8.
Leuchter A, Simon S, Daly K, Abrams M, Rosenberg-Thompson S, Dunkin J, et al.
Am J Geriatr Psychiatry . 2017 May; 2(4):290-299. PMID: 28530979
The authors examined quantitative electroencephalographc (QEEG) coherence in 37 depressed elderly patients and performed 2-year follow-up evaluations. All subjects had equivocal cognitive impairment, but none had delirium or dementia. More...
9.
Leuchter A, Simon S, Daly K, Rosenberg-Thompson S, Abrams M, Dunkin J, et al.
Am J Geriatr Psychiatry . 2017 May; 2(3):200-209. PMID: 28530933
Using quantitative electroencephalographic coherence (a measure of synchronized electrical activity between brain regions) the authors examined heterogeneity in clinical presentation and outcome inpatients with dementia. Patients (N = 114) with...
10.
Mahoney 3rd J, Haile C, De La Garza 2nd R, Thakkar H, Newton T
Am J Addict . 2017 Mar; 26(3):221-227. PMID: 28248441
Background And Objectives: Chronic cocaine use has been linked to several abnormalities in cardiac functioning. The objective of this study was to further characterize baseline heart rate and electrocardiograph (ECG)...