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Thomas Eckert

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Recent Articles
1.
Eckert T, Zobaer M, Boulos J, Alexander-Bryant A, Baker T, Rivers C, et al.
Cancers (Basel) . 2025 Feb; 17(3). PMID: 39941829
Background: Glioblastoma (GBM) is the most common primary malignant brain tumor, with fewer than 5% of patients surviving five years after diagnosis. The introduction of immune checkpoint inhibitors (ICIs), followed...
2.
Zhang N, Li L, Mohri M, Siebert S, Lutteke T, Louton H, et al.
Int J Biol Macromol . 2024 Aug; 279(Pt 1):134951. PMID: 39179069
The structural dynamics of the interactions between defensins or lysozymes and various saccharide chains that are covalently linked to lipids or proteins were analyzed in relation to the sub-molecular architecture...
3.
Hendrix A, Eckert T, Kerrison C, Carlyle L, Yan A
Cureus . 2024 May; 16(4):e58193. PMID: 38741863
In the list of top 10 causes of death worldwide in 2019, stroke ranks number two, with a recent uptick in incidence involving younger adults. While common risk factors like...
4.
Siebert H, Eckert T, Bhunia A, Klatte N, Mohri M, Siebert S, et al.
Biomedicines . 2023 May; 11(5). PMID: 37239092
The global outbreak of SARS-CoV-2/COVID-19 provided the stage to accumulate an enormous biomedical data set and an opportunity as well as a challenge to test new concepts and strategies to...
5.
Eckert T, von Cosel J, Kamps B, Siebert H, Zhang R, Zhang N, et al.
Front Mol Biosci . 2021 Dec; 8:756701. PMID: 34869589
The collagen-integrin interactions are mediated by the doubly charged Mg cation. In nature this cation seems to have the optimal binding strength to stabilize this complex. It is essential that...
6.
Eckert T, Jahrling-Butkus M, Louton H, Burg-Roderfeld M, Zhang R, Zhang N, et al.
Mar Drugs . 2021 Oct; 19(10). PMID: 34677442
Osteoarthritis belongs to the most common joint diseases in humans and animals and shows increased incidence in older patients. The bioactivities of collagen hydrolysates, sulfated glucosamine and a special fatty...
7.
Zhang R, Jin L, Zhang N, Petridis A, Eckert T, Scheiner-Bobis G, et al.
Mar Drugs . 2019 Aug; 17(8). PMID: 31409009
Formulas derived from theoretical physics provide important insights about the nematocyst discharge process of Cnidaria (Hydra, jellyfishes, box-jellyfishes and sea-anemones). Our model description of the fastest process in living nature...
8.
Zhang R, Zhang N, Mohri M, Wu L, Eckert T, Krylov V, et al.
ACS Omega . 2019 Mar; 4(2):4206-4220. PMID: 30847433
Insulin and lysozyme share the common features of being prone to aggregate and having biomedical importance. Encapsulating lysozyme and insulin in micellar nanoparticles probably would prevent aggregation and facilitate oral...
9.
Eckert T, Goericke-Pesch S, Heydel C, Bergmann M, Kauffold J, Failing K, et al.
BMC Microbiol . 2019 Jan; 19(1):23. PMID: 30683062
Background: Interaction of spermatozoa and Chlamydiae spp. might contribute to reduced fertility in cattle. To proof this hypothesis, bovine semen was incubated with viable or heat inactivated Chlamydia (C.) abortus...
10.
Kunzle M, Eckert T, Beck T
Inorg Chem . 2018 Oct; 57(21):13431-13436. PMID: 30351078
Protein containers are suitable building blocks for bioinorganic materials. Here, we show that high concentrations of magnesium ions induce the formation of a unitary protein scaffold, whereas low magnesium concentration...