David Eidelberg
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Explore the profile of David Eidelberg including associated specialties, affiliations and a list of published articles.
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247
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7356
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Recent Articles
1.
Clinical and brain functional correlates of instrumental rigidity measurement in Parkinson's disease
Nakano Y, Hirano S, Tamura M, Koizumi Y, Kitayama Y, Izumi M, et al.
Sci Rep
. 2025 Mar;
15(1):8056.
PMID: 40055432
Rigidity, a cardinal symptom of Parkinson's disease (PD), remains challenging to assess objectively. A torque-angle instrument was developed to quantify muscle tone, providing two parameters: bias difference and elastic coefficient....
2.
Tang C, Nakano Y, Vo A, Nguyen N, Schindlbeck K, Mattis P, et al.
Nat Commun
. 2024 Dec;
15(1):10797.
PMID: 39737936
Isolated rapid eye movement sleep behavior disorder is a prodrome of α-synucleinopathies. Using positron emission tomography, we assessed changes in Parkinson's disease-related motor and cognitive metabolic networks and caudate/putamen dopaminergic...
3.
A candidate loss-of-function variant in SGIP1 causes synaptic dysfunction and recessive parkinsonism
Decet M, Scott P, Kuenen S, Meftah D, Swerts J, Calatayud C, et al.
Cell Rep Med
. 2024 Sep;
5(10):101749.
PMID: 39332416
Synaptic dysfunction is recognized as an early step in the pathophysiology of parkinsonism. Several genetic mutations affecting the integrity of synaptic proteins cause or increase the risk of developing disease....
4.
Palandira S, Falvey A, Carrion J, Zeng Q, Chaudhry S, Grossman K, et al.
bioRxiv
. 2024 Sep;
PMID: 39282308
Background: Acute liver injury (ALI) that progresses into acute liver failure (ALF) is a life-threatening condition with an increasing incidence and associated costs. Acetaminophen (N-acetyl-p-aminophenol, APAP) overdosing is among the...
5.
Buchert R, Huppertz H, Wegner F, Berding G, Brendel M, Apostolova I, et al.
J Neurol Neurosurg Psychiatry
. 2024 Aug;
PMID: 39107038
Background: Diagnostic criteria for progressive supranuclear palsy (PSP) include midbrain atrophy in MRI and hypometabolism in [F]fluorodeoxyglucose (FDG)-positron emission tomography (PET) as supportive features. Due to limited data regarding their...
6.
Brumberg J, Blazhenets G, Buhler S, Fostitsch J, Rijntjes M, Ma Y, et al.
Ann Neurol
. 2024 Jun;
96(3):539-550.
PMID: 38888141
Objective: Patients with Lewy body diseases have an increased risk of dementia, which is a significant predictor for survival. Posterior cortical hypometabolism on [F]fluorodeoxyglucose positron emission tomography (PET) precedes the...
7.
Eidelberg D, Tang C, Nakano Y, Vo A, Nguyen N, Schindlbeck K, et al.
Res Sq
. 2024 Jun;
PMID: 38853923
Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal syndrome for Parkinson's disease (PD) and related -synucleinopathies. We conducted a longitudinal imaging study of network changes in iRBD...
8.
Unadkat P, Vo A, Ma Y, Peng S, Nguyen N, Niethammer M, et al.
Res Sq
. 2024 May;
PMID: 38766007
Subthalamic nucleus deep brain stimulation (STN-DBS) alleviates motor symptoms of Parkinson's disease (PD), thereby improving quality of life. However, quantitative brain markers to evaluate DBS responses and select suitable patients...
9.
Barbero J, Unadkat P, Choi Y, Eidelberg D
Neurotherapeutics
. 2023 Sep;
20(6):1653-1668.
PMID: 37684533
Network analysis of functional brain scans acquired with [F]-fluorodeoxyglucose positron emission tomography (FDG PET, to map cerebral glucose metabolism), or resting-state functional magnetic resonance imaging (rs-fMRI, to map blood oxygen...
10.
Spetsieris P, Eidelberg D
Neuroimage Clin
. 2023 Sep;
39:103488.
PMID: 37660556
Notable success has been achieved in the study of neurodegenerative conditions using reduction techniques such as principal component analysis (PCA) and sparse inverse covariance estimation (SICE) in positron emission tomography...