Thomas Drepper
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Explore the profile of Thomas Drepper including associated specialties, affiliations and a list of published articles.
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77
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1303
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Recent Articles
1.
Knapp F, Hogenkamp F, Paik S, Jaeger K, Pietruszka J, Drepper T
Methods Mol Biol
. 2024 Dec;
2840:133-148.
PMID: 39724349
Photocaged compounds are chemical conjugates that are designed to release an active molecule upon exposure to light of a specific wavelength. In recent years, photocaged inducer molecules such as caged...
2.
Lenz P, Bakkes P, Muller C, Malek M, Freudl R, Oldiges M, et al.
Microb Cell Fact
. 2023 Oct;
22(1):203.
PMID: 37805580
Background: Bacillus subtilis is one of the workhorses in industrial biotechnology and well known for its secretion potential. Efficient secretion of recombinant proteins still requires extensive optimization campaigns and screening...
3.
Bitzenhofer N, Hofel C, Thies S, Weiler A, Eberlein C, Heipieper H, et al.
Microb Biotechnol
. 2023 Jul;
17(1):e14312.
PMID: 37435812
Pseudomonas species have become promising cell factories for the production of natural products due to their inherent robustness. Although these bacteria have naturally evolved strategies to cope with different kinds...
4.
Kasahara K, Leygeber M, Seiffarth J, Ruzaeva K, Drepper T, Noh K, et al.
Front Microbiol
. 2023 Jul;
14:1198170.
PMID: 37408642
Microfluidic cultivation devices that facilitate O control enable unique studies of the complex interplay between environmental O availability and microbial physiology at the single-cell level. Therefore, microbial single-cell analysis based...
5.
Weihmann R, Kubicki S, Bitzenhofer N, Domrose A, Bator I, Kirschen L, et al.
FEMS Microbes
. 2023 Jun;
4:xtac030.
PMID: 37333445
The expression of biosynthetic genes in bacterial hosts can enable access to high-value compounds, for which appropriate molecular genetic tools are essential. Therefore, we developed a toolbox of modular vectors,...
6.
Hilgers F, Hogenkamp F, Klaus O, Kruse L, Loeschcke A, Bier C, et al.
Front Bioeng Biotechnol
. 2022 Oct;
10:902059.
PMID: 36246361
Photocaged inducer molecules, especially photocaged isopropyl-β-d-1-thiogalactopyranoside (cIPTG), are well-established optochemical tools for light-regulated gene expression and have been intensively applied in and other bacteria including or . In this study,...
7.
Bitzenhofer N, Hilgers F, Bosio G, Torra J, Casini G, Beinlich F, et al.
Methods Mol Biol
. 2022 Sep;
2564:143-183.
PMID: 36107341
Flavin-based fluorescent proteins (FbFPs), a class of small fluorescent proteins derived from light-oxygen-voltage (LOV) domains, bind ubiquitous endogenous flavins as chromophores. Due to their unique properties, they can be used...
8.
Klaus O, Hilgers F, Nakielski A, Hasenklever D, Jaeger K, Axmann I, et al.
Curr Opin Biotechnol
. 2022 Aug;
77:102764.
PMID: 35932511
With more than 80 000 compounds, terpenoids represent one of the largest classes of secondary metabolites naturally produced by various plants and other organisms. Owing to the tremendous structural diversity,...
9.
Loeschcke A, Hage-Hulsmann J, Troost K, Wewer V, Jaeger K, Drepper T
Methods Mol Biol
. 2022 Feb;
2379:125-154.
PMID: 35188660
Terpenes are one of the largest classes of secondary metabolites that occur in all kingdoms of life and offer diverse valuable properties for food and pharma industry including pleasant odor...
10.
Hogenkamp F, Hilgers F, Bitzenhofer N, Ophoven V, Haase M, Bier C, et al.
Chembiochem
. 2021 Nov;
23(1):e202100467.
PMID: 34750949
Photocaged compounds are applied for implementing precise, optochemical control of gene expression in bacteria. To broaden the scope of UV-light-responsive inducer molecules, six photocaged carbohydrates were synthesized and photochemically characterized,...