Thomas Dechat
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Explore the profile of Thomas Dechat including associated specialties, affiliations and a list of published articles.
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24
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2190
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Recent Articles
1.
Blouin S, Hartmann M, Fratzl-Zelman N, Messmer P, Whisenant D, Erdos M, et al.
Aging Dis
. 2024 Nov;
PMID: 39571160
Hutchison-Gilford progeria syndrome (HGPS) is a rare genetic disease caused by a mutation in LMNA, the gene encoding A-type lamins, leading to premature aging with severely reduced life span. HGPS...
2.
Schamberger B, Ehrig S, Dechat T, Spitzer S, Bidan C, Fratzl P, et al.
PNAS Nexus
. 2024 Apr;
3(4):pgae121.
PMID: 38590971
Little is known about the contribution of 3D surface geometry to the development of multilayered tissues containing fibrous extracellular matrix components, such as those found in bone. In this study,...
3.
Werzowa J, Behanova M, Handisurya A, Heger F, Indra A, Holzer B, et al.
J Clin Med
. 2023 Aug;
12(15).
PMID: 37568385
It is not well established to what extent previous immunizations offer protection against infections with the SARS-CoV-2 Omicron variant in dialysis patients. We aimed to define the relevant humoral response...
4.
Ruiss M, Kronschlager M, Schlatter A, Dechat T, Findl O
Sci Rep
. 2021 Dec;
11(1):23406.
PMID: 34862438
At the moment, cataract, which is the opacification of the eye's lens, can only be treated by surgery. In order to develop and test new pharmacological treatment strategies for the...
5.
Naetar N, Georgiou K, Knapp C, Bronshtein I, Zier E, Fichtinger P, et al.
Elife
. 2021 Feb;
10.
PMID: 33605210
Lamins form stable filaments at the nuclear periphery in metazoans. Unlike B-type lamins, lamins A and C localize also in the nuclear interior, where they interact with lamin-associated polypeptide 2...
6.
Kronschlager M, Ruiss M, Dechat T, Findl O
Acta Ophthalmol
. 2020 Oct;
99(4):e587-e593.
PMID: 33124749
Purpose: The aim of the present study was to determine whether caffeine concentrations in human lens epithelial cells (LECs) achieved from acute peroral caffeine intake inhibit ultraviolet radiation-induced apoptosis in...
7.
Vidak S, Georgiou K, Fichtinger P, Naetar N, Dechat T, Foisner R
J Cell Sci
. 2018 Jan;
131(3).
PMID: 29361532
A-type lamins are components of the peripheral nuclear lamina but also localize in the nuclear interior in a complex with lamina-associated polypeptide (LAP) 2α. Loss of LAP2α and nucleoplasmic lamins...
8.
Allmaier G, Blaas D, Bliem C, Dechat T, Fedosyuk S, Gosler I, et al.
J Virol Methods
. 2017 Oct;
251:15-21.
PMID: 28966037
For vaccine development, 3D-structure determination, direct fluorescent labelling, and numerous other studies, homogeneous virus preparations of high purity are essential. Working with human rhinoviruses (RVs), members of the picornavirus family...
9.
Elling U, Wimmer R, Leibbrandt A, Burkard T, Michlits G, Leopoldi A, et al.
Nature
. 2017 Sep;
550(7674):114-118.
PMID: 28953874
The ability to directly uncover the contributions of genes to a given phenotype is fundamental for biology research. However, ostensibly homogeneous cell populations exhibit large clonal variance that can confound...
10.
Gesson K, Rescheneder P, Skoruppa M, von Haeseler A, Dechat T, Foisner R
Genome Res
. 2016 Jan;
26(4):462-73.
PMID: 26798136
Lamins are components of the peripheral nuclear lamina and interact with heterochromatic genomic regions, termed lamina-associated domains (LADs). In contrast to lamin B1 being primarily present at the nuclear periphery,...