Thomas D Stamato
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Explore the profile of Thomas D Stamato including associated specialties, affiliations and a list of published articles.
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10
Citations
491
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Recent Articles
1.
Croco E, Marchionni S, Storci G, Bonafe M, Franceschi C, Stamato T, et al.
Biogerontology
. 2017 Jun;
18(4):485-497.
PMID: 28573417
In evolutionary terms, life on the planet has taken the form of independently living cells for the majority of time. In comparison, the mammalian radiation is a relatively recent event....
2.
Lorenzini A, Johnson F, Oliver A, Tresini M, Smith J, Hdeib M, et al.
Mech Ageing Dev
. 2009 Nov;
130(11-12):784-92.
PMID: 19896964
The identification of the cellular mechanisms responsible for the wide differences in species lifespan remains one of the major unsolved problems of the biology of aging. We measured the capacity...
3.
Ramalingam A, Farmer G, Stamato T, Prendergast G
Cell Cycle
. 2007 Aug;
6(15):1914-8.
PMID: 17671430
The Bin1 gene encodes a BAR adapter protein that suppresses cancer by poorly defined mechanisms. In an effort to gain insights, we identified cellular proteins that form biochemical complexes with...
4.
Ayene I, Biaglow J, Kachur A, Stamato T, Koch C
J Cell Biochem
. 2007 May;
103(1):123-35.
PMID: 17516514
More than 400 million people are susceptible to oxidative stress due to glucose-6-phosphate dehydrogenase (G6PD) deficiency. Protein glutathionylation is believed to be responsible for loss of protein function and/or cellular...
5.
Morrish T, Garcia-Perez J, Stamato T, Taccioli G, Sekiguchi J, Moran J
Nature
. 2007 Mar;
446(7132):208-12.
PMID: 17344853
Long interspersed element-1 (LINE-1 or L1) elements are abundant, non-long-terminal-repeat (non-LTR) retrotransposons that comprise approximately 17% of human DNA. The average human genome contains approximately 80-100 retrotransposition-competent L1s (ref. 2),...
6.
Biaglow J, Ayene I, Koch C, Donahue J, Stamato T, Mieyal J, et al.
Radiat Res
. 2003 Mar;
159(4):484-94.
PMID: 12643793
The major focus of this work was to investigate how altered protein thiol redox homeostasis affects radiation-induced cell death. We used the cells of wild-type CHO cell line K1, the...
7.
Mauldin S, Getts R, Liu W, Stamato T
Nucleic Acids Res
. 2002 Sep;
30(18):4075-87.
PMID: 12235392
We find that nuclear protein extracts from mammalian cells contain an activity that allows DNA ends to associate with circular pUC18 plasmid DNA. This activity requires the catalytic subunit of...
8.
Delacote F, Han M, Stamato T, Jasin M, Lopez B
Nucleic Acids Res
. 2002 Jul;
30(15):3454-63.
PMID: 12140331
Non-homologous end joining (NHEJ) and homologous recombination (HR) are two alternative/competitor pathways for the repair of DNA double-strand breaks (DSBs). To gain further insights into the regulation of DSB repair,...
9.
Morrish T, Gilbert N, Myers J, Vincent B, Stamato T, Taccioli G, et al.
Nat Genet
. 2002 May;
31(2):159-65.
PMID: 12006980
Long interspersed elements (LINE-1s) are abundant retrotransposons in mammalian genomes that probably retrotranspose by target site-primed reverse transcription (TPRT). During TPRT, the LINE-1 endonuclease cleaves genomic DNA, freeing a 3'...
10.
Ayene I, Stamato T, Mauldin S, Biaglow J, Tuttle S, Jenkins S, et al.
J Biol Chem
. 2002 Jan;
277(12):9929-35.
PMID: 11788599
Glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the oxidative pentose phosphate cycle, regulates the NADPH/NADP(+) ratio in eukaryotic cells. G6PD deficiency is one of the most common mutations in humans...