Thomas C Smyrk
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Explore the profile of Thomas C Smyrk including associated specialties, affiliations and a list of published articles.
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309
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12135
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Recent Articles
1.
Urquhart S, Smyrk T, Harmsen W, Loftus Jr E, Kisiel J, Coelho-Prabhu N
Crohns Colitis 360
. 2025 Feb;
7(1):otaf001.
PMID: 39959612
Background: Patients with Crohn's disease (CD) who have ileal or any small bowel (SB) involvement are at increased risk of developing SB cancer. Due to the rarity of this complication...
2.
Sigafoos A, Tolosa E, Carr R, Fernandez-Barrena M, Almada L, Pease D, et al.
Cancer Res Commun
. 2024 Jun;
4(7):1677-1689.
PMID: 38896052
Aberrant activation of GLI transcription factors has been implicated in the pathogenesis of different tumor types including pancreatic ductal adenocarcinoma. However, the mechanistic link with established drivers of this disease...
3.
Bamidele A, Mishra S, Piovezani Ramos G, Hirsova P, Klatt E, Abdelrahman L, et al.
Gastroenterology
. 2024 Jan;
166(5):826-841.e19.
PMID: 38266738
Background & Aims: Incapacitated regulatory T cells (Tregs) contribute to immune-mediated diseases. Inflammatory Tregs are evident during human inflammatory bowel disease; however, mechanisms driving the development of these cells and...
4.
Bach C, Sheedy S, Heiken J, Graham R, Moreira R, Smyrk T, et al.
Abdom Radiol (NY)
. 2023 Dec;
49(2):375-383.
PMID: 38127281
Purpose: The purpose of this study is to determine computed tomography (CT) findings that aid in differentiating idiopathic myointimal hyperplasia of mesenteric veins (IMHMV) from other colitides. Methods: Retrospective review...
5.
Gleeson F, Smyrk T, Hansel S
Gastroenterology
. 2022 Nov;
164(6):e17-e18.
PMID: 36395871
No abstract available.
6.
Piovezani Ramos G, Bamidele A, Klatt E, Sagstetter M, Kurdi A, Hamdan F, et al.
Gastroenterology
. 2022 Oct;
164(2):256-271.e10.
PMID: 36272457
Background & Aims: Although T-cell intrinsic expression of G9a has been associated with murine intestinal inflammation, mechanistic insight into the role of this methyltransferase in human T-cell differentiation is ill...
7.
Wang L, Mara K, Ravi K, Wu T, Smyrk T, Katzka D, et al.
Aliment Pharmacol Ther
. 2022 Sep;
56(10):1444-1452.
PMID: 36163696
Background: Dietary therapy successfully treats eosinophilic oesophagitis (EoE), but limited data exist on predictors of patient response. Aims: To determine response rates and to identify predictors of histologic response to...
8.
Sinicrope F, Shi Q, Catteau A, Poage G, Zemla T, Mlecnik B, et al.
JCO Precis Oncol
. 2022 Aug;
6:e2200010.
PMID: 35952316
Purpose: The recommended duration of adjuvant fluoropyrimidine and oxaliplatin chemotherapy for patients with stage III colon cancer is based on tumor classification into clinically low-risk (T N) and high-risk (T...
9.
Holtz L, Hoffmann J, Linneman L, He M, Smyrk T, Liu T, et al.
Front Pediatr
. 2022 Apr;
10:874116.
PMID: 35463906
Background And Aim: We sought to correlate two different measures of gut permeability [lactulose:mannitol (L:M) and lactulose:rhamnose (L:R)] to the severity of duodenal histopathology in children with and without elevated...
10.
Gits H, Tang A, Harmsen W, Bamlet W, Graham R, Petersen G, et al.
J Gastrointest Oncol
. 2021 Nov;
12(5):2275-2286.
PMID: 34790392
Background: Previous reports suggest that intact SMAD4 expression is associated with a locally aggressive pancreas cancer phenotype. The objectives of this work were to determine the frequency of intact SMAD4...