Thomas Bouckenooghe
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Explore the profile of Thomas Bouckenooghe including associated specialties, affiliations and a list of published articles.
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18
Citations
842
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Recent Articles
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Brom M, Woliner-van der Weg W, Joosten L, Frielink C, Bouckenooghe T, Rijken P, et al.
Diabetologia
. 2014 Feb;
57(5):950-9.
PMID: 24488022
Aims/hypothesis: A reliable method for in vivo quantification of pancreatic beta cell mass (BCM) could lead to further insight into the pathophysiology of diabetes. The glucagon-like peptide 1 receptor, abundantly...
3.
Bouckenooghe T, Sisino G, Aurientis S, Chinetti-Gbaguidi G, Kerr-Conte J, Staels B, et al.
Biochim Biophys Acta
. 2013 Dec;
1842(4):584-93.
PMID: 24361460
Background: Obesity, characterized by low grade inflammation, induces adipose tissue macrophage (ATM) infiltration in white adipose tissue (AT) in both humans and rodents, thus contributing to insulin resistance. Previous studies...
4.
Sisino G, Bouckenooghe T, Aurientis S, Fontaine P, Storme L, Vambergue A
Biochim Biophys Acta
. 2013 Jul;
1832(12):1959-68.
PMID: 23872577
Growing evidence indicates that maternal pathophysiological conditions, such as diabetes, influence fetal growth and could program metabolic disease in adulthood. Placental cells, particularly Hofbauer cells (HBCs), which are placental macrophages...
5.
Ivars J, Butruille L, Knauf C, Bouckenooghe T, Mayeur S, Vieau D, et al.
Peptides
. 2012 Mar;
35(1):136-8.
PMID: 22446510
Apelin and its receptor APJ are expressed in fetal tissues but their function and regulation remain largely unknown. In rat, maternal treatment with a nitric oxide synthase inhibitor inducing hypertension...
6.
Eizirik D, Sammeth M, Bouckenooghe T, Bottu G, Sisino G, Igoillo-Esteve M, et al.
PLoS Genet
. 2012 Mar;
8(3):e1002552.
PMID: 22412385
Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic beta cells are killed by infiltrating immune cells and by cytokines released by these cells. Signaling events occurring in...
7.
Roche S, DIppolito G, Gomez L, Bouckenooghe T, Lehmann S, Montero-Menei C, et al.
Int J Pharm
. 2012 Jan;
440(1):72-82.
PMID: 22285475
Several mechanisms mediate the regenerative and reparative capacity of stem cells, including cytokine secretion; therefore these cells can act as delivery systems of therapeutic molecules. Here we begin to address...
8.
Arif S, Moore F, Marks K, Bouckenooghe T, Dayan C, Planas R, et al.
Diabetes
. 2011 Jun;
60(8):2112-9.
PMID: 21659501
Objective: CD4 T-cells secreting interleukin (IL)-17 are implicated in several human autoimmune diseases, but their role in type 1 diabetes has not been defined. To address the relevance of such...
9.
Theys N, Ahn M, Bouckenooghe T, Reusens B, Remacle C
J Nutr Biochem
. 2010 Dec;
22(10):985-94.
PMID: 21190832
Accumulating evidence has shown that maternal malnutrition increases the risk of metabolic disease in the progeny. We previously reported that prenatal exposure to a low-protein diet (LP) leads to mitochondrial...
10.
Moore F, Naamane N, Colli M, Bouckenooghe T, Ortis F, Gurzov E, et al.
J Biol Chem
. 2010 Oct;
286(2):929-41.
PMID: 20980260
Cytokines produced by islet-infiltrating immune cells induce β-cell apoptosis in type 1 diabetes. The IFN-γ-regulated transcription factors STAT1/IRF-1 have apparently divergent effects on β-cells. Thus, STAT1 promotes apoptosis and inflammation,...