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Thomas A Robertson

Explore the profile of Thomas A Robertson including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
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Recent Articles
1.
Sinnollareddy M, Roberts M, Lipman J, Robertson T, Peake S, Roberts J
Int J Antimicrob Agents . 2014 Dec; 45(2):192-5. PMID: 25455854
Fluconazole is a widely used antifungal agent in critically ill patients. It is predominantly (60-80%) excreted unchanged in urine. Sustained low-efficiency diafiltration (SLED-f) is increasingly being utilised in critically ill...
2.
Sime F, Roberts M, Roberts J, Robertson T
J Chromatogr B Analyt Technol Biomed Life Sci . 2014 May; 960:134-44. PMID: 24814000
There is strong evidence in literature supporting the benefit of monitoring plasma concentrations of β-lactam antibiotics in the critically ill to ensure appropriateness of dosing. The objective of this work...
3.
Robertson T, Bunel F, Roberts M
Cells . 2014 Apr; 2(3):591-606. PMID: 24709799
Intravital fluorescence microscopy enables the direct imaging of fluorophores in vivo and advanced techniques such as fluorescence lifetime imaging (FLIM) enable the simultaneous detection of multiple fluorophores. Consequently, it is...
4.
Sime F, Roberts M, Warner M, Hahn U, Robertson T, Yeend S, et al.
Antimicrob Agents Chemother . 2014 Apr; 58(6):3533-7. PMID: 24687508
This study assessed the pharmacokinetics and dosing adequacy of piperacillin in febrile neutropenic patients after the first dose. Pharmacokinetic analysis was performed using noncompartmental methods. We observed an elevated volume...
5.
Wong G, Brinkman A, Benefield R, Carlier M, De Waele J, El Helali N, et al.
J Antimicrob Chemother . 2014 Jan; 69(5):1416-23. PMID: 24443514
Objectives: Emerging evidence supports the use of therapeutic drug monitoring (TDM) of β-lactams for intensive care unit (ICU) patients to optimize drug exposure, although limited detail is available on how...
6.
Carson K, Brinn M, Robertson T, To-A-Nan R, Esterman A, Peters M, et al.
Subst Abuse . 2013 Jun; 7:85-105. PMID: 23772176
Tobacco smoking remains the single most preventable cause of morbidity and mortality in developed countries and poses a significant threat across developing countries where tobacco use prevalence is increasing. Nicotine...
7.
Li P, Robertson T, Zhang Q, Fletcher L, Crawford D, Weiss M, et al.
Pharm Res . 2012 Feb; 29(6):1658-69. PMID: 22302523
Purpose: To explore how liver damage arising from cardio-hepatic syndromes in RHF affect the hepatic pharmacokinetics of basic drugs. Methods: The hepatic pharmacokinetics of five selected basic drugs with different...
8.
Lin L, Grice J, Butler M, Zvyagin A, Becker W, Robertson T, et al.
Pharm Res . 2011 Jul; 28(11):2920-30. PMID: 21717255
Purpose: There is a lack of relevant, non-animal alternatives for assessing exposure and toxicity of nanoparticle-containing cosmetics, e.g. sunscreens. Our goal was to evaluate timecorrelated single photon counting (TCSPC) for...
9.
Fanning K, Robertson T, Prins J, Roberts M
Antimicrob Agents Chemother . 2011 Mar; 55(6):3008-11. PMID: 21402839
This work sought to define how pancreatitis affected antibiotic distribution in a perfused rat pancreas model. The distribution kinetics of four antibiotics were examined in control animals and animals with...
10.
Robertson T, Sanchez W, Roberts M
J Biomed Nanotechnol . 2011 Feb; 6(5):452-68. PMID: 21329041
There are a growing number of commercial uses of nanoparticles which involve direct people contact with the potential for absorption through the skin. Nanoparticles are present in a range of...