Thomas A Gorr
Overview
Explore the profile of Thomas A Gorr including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
806
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Recent Articles
1.
Armbruster J, Aboouf M, Gassmann M, Egert A, Schorle H, Hornung V, et al.
PLoS One
. 2024 Dec;
19(12):e0316741.
PMID: 39729522
[This corrects the article DOI: 10.1371/journal.pone.0275725.].
2.
Aboouf M, Gorr T, Hamdy N, Gassmann M, Thiersch M
Cells
. 2023 Sep;
12(18).
PMID: 37759463
Brown adipose tissue (BAT) plays an important role in energy homeostasis by generating heat from chemical energy via uncoupled oxidative phosphorylation. Besides its high mitochondrial content and its exclusive expression...
3.
Aboouf M, Armbruster J, Guscetti F, Thiersch M, Boss A, Godecke A, et al.
Sci Rep
. 2023 May;
13(1):7530.
PMID: 37161046
Myoglobin (MB) is expressed in different cancer types and may act as a tumor suppressor in breast cancer. The mechanisms by which basal MB expression level impacts murine mammary tumorigenesis...
4.
Aboouf M, Armbruster J, Thiersch M, Guscetti F, Kristiansen G, Schraml P, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232784
The expression of myoglobin (MB), well known as the oxygen storage and transport protein of myocytes, is a novel hallmark of the luminal subtype in breast cancer patients and correlates...
5.
Armbruster J, Aboouf M, Gassmann M, Egert A, Schorle H, Hornung V, et al.
PLoS One
. 2022 Oct;
17(10):e0275725.
PMID: 36223378
Myoglobin (MB) is known to bind and deliver oxygen in striated muscles at high expression levels. MB is also expressed at much reduced levels in mammary epithelial cells, where the...
6.
Aboouf M, Armbruster J, Thiersch M, Gassmann M, Godecke A, Gnaiger E, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 Aug;
1866(12):159026.
PMID: 34384891
The identification of novel physiological regulators that stimulate energy expenditure through brown adipose tissue (BAT) activity in substrate catalysis is of utmost importance to understand and treat metabolic diseases. Myoglobin...
7.
Ademi H, Shinde D, Gassmann M, Gerst D, Chaachouay H, Vogel J, et al.
PLoS One
. 2021 May;
16(5):e0251765.
PMID: 33999935
Since growing tumors stimulate angiogenesis, via vascular endothelial growth factor (VEGF), angiogenesis inhibitors (AIs, blockers of the VEGF signaling pathway) have been introduced to cancer therapy. However, AIs often yielded...
8.
Bronnimann D, Annese T, Gorr T, Djonov V
J Exp Biol
. 2018 Jun;
221(Pt 15).
PMID: 29903841
Nucleated circulating red blood cells (RBCs) of developing zebrafish, chick and mouse embryos can actively proliferate. While marrow- or organ-mediated erythropoiesis has been widely studied, transforming processes of circulating RBCs...
9.
Misra T, Baccino-Calace M, Meyenhofer F, Rodriguez-Crespo D, Akarsu H, Armenta-Calderon R, et al.
Biol Open
. 2016 Dec;
6(2):296-304.
PMID: 28011628
Cells experience different oxygen concentrations depending on location, organismal developmental stage, and physiological or pathological conditions. Responses to reduced oxygen levels (hypoxia) rely on the conserved hypoxia-inducible factor 1 (HIF-1)....
10.
Meller S, VAN Ellen A, Gevensleben H, Bicker A, Hankeln T, Gorr T, et al.
Anticancer Res
. 2016 Dec;
36(12):6235-6241.
PMID: 27919941
Background/aim: Ectopic myoglobin (MB) expression, mediated by alternative and hypoxia-inducible transcription, has recently been demonstrated in several epithelial tumours. This study aimed to examine the expression of MB in hormone-independent...