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Thomas A Davis

Explore the profile of Thomas A Davis including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 110
Citations 3870
Followers 0
Related Specialties
Orthopedics
Oncology
General Surgery
Top 10 Co-Authors
Eric A Elster
Jonathan A Forsberg
Benjamin K Potter
Benjamin Levi
Devaveena Dey
Ammar T Qureshi
Matthew J Bradley
Shailesh Agarwal
Cassie J Rowe
Trevor S Brown
Published In
Bone
Environ Sci Technol
J Inflamm (Lond)
Clin Orthop Relat Res
J Orthop Res
Affiliations
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Recent Articles
1.
Systemic inflammation following traumatic injury and its impact on neuroinflammatory gene expression in the rodent brain
Rowe C, Nwaolu U, Martin L, Huang B, Mang J, Salinas D, et al.
J Neuroinflammation . 2024 Aug; 21(1):211. PMID: 39198925
Background: Trauma can result in systemic inflammation that leads to organ dysfunction, but the impact on the brain, particularly following extracranial insults, has been largely overlooked. Methods: Building upon our...
2.
Missing in action: A bibliometric analysis of military research in the medical literature since 1950
Lile D, Bergman A, Rolfing J, Allard R, Davis T, Gross K, et al.
J Trauma Acute Care Surg . 2024 May; 97(2S Suppl 1):S14-S18. PMID: 38750632
Background: Top-tier general and specialty scientific journals serve as a bellwether for national research priorities. We hypothesize that military-relevant publications are underrepresented in the scientific literature and that such publications...
3.
The influence of microbial colonization on inflammatory versus pro-healing trajectories in combat extremity wounds
Schobel S, Gann E, Unselt D, Grey S, Lisboa F, Upadhyay M, et al.
Sci Rep . 2024 Mar; 14(1):5006. PMID: 38438404
A combination of improved body armor, medical transportation, and treatment has led to the increased survival of warfighters from combat extremity injuries predominantly caused by blasts in modern conflicts. Despite...
4.
Cutaneous burn injury represents a major risk factor for the development of traumatic ectopic bone formation following blast-related extremity injury
Rowe C, Nwaolu U, Salinas D, Lansford J, McCarthy C, Anderson J, et al.
Bone . 2024 Feb; 181:117029. PMID: 38331307
Blast-related traumatic heterotopic ossification (tHO) impacts clinical outcomes in combat-injured patients, leading to delayed wound healing, inflammatory complications, and reduced quality of life. Blast injured patients often have significant burns....
5.
Inhibition of focal adhesion kinase 2 results in a macrophage polarization shift to M2 which attenuates local and systemic inflammation and reduces heterotopic ossification after polysystem extremity trauma
Rowe C, Nwaolu U, Salinas D, Hong J, Nunez J, Lansford J, et al.
Front Immunol . 2023 Dec; 14:1280884. PMID: 38116014
Introduction: Heterotopic ossification (HO) is a complex pathology often observed in combat injured casualties who have sustained severe, high energy polytraumatic extremity injuries. Once HO has developed, prophylactic therapies are...
6.
Systemic inflammation induced from remote extremity trauma is a critical driver of secondary brain injury
Rowe C, Mang J, Huang B, Dommaraju K, Potter B, Schobel S, et al.
Mol Cell Neurosci . 2023 Jul; 126:103878. PMID: 37451414
Blast exposure, commonly experienced by military personnel, can cause devastating life-threatening polysystem trauma. Despite considerable research efforts, the impact of the systemic inflammatory response after major trauma on secondary brain...
7.
Systematic Identification of the Optimal Housekeeping Genes for Accurate Transcriptomic and Proteomic Profiling of Tissues following Complex Traumatic Injury
Dragon A, Rowe C, Rhodes A, Pak O, Davis T, Ronzier E
Methods Protoc . 2023 Mar; 6(2). PMID: 36961042
Trauma triggers critical molecular and cellular signaling cascades that drive biological outcomes and recovery. Variations in the gene expression of common endogenous reference housekeeping genes (HKGs) used in data normalization...
8.
Tourniquet-induced ischemia creates increased risk of organ dysfunction and mortality following delayed limb amputation
Rowe C, Walsh S, Dragon A, Rhodes A, Pak O, Ronzier E, et al.
Injury . 2023 Mar; PMID: 36906480
Tourniquets are critical for the control of traumatic extremity hemorrhage. In this study, we sought to determine, in a rodent blast-related extremity amputation model, the impact of prolonged tourniquet application...
9.
Tourniquet use following blast-associated complex lower limb injury and traumatic amputation promotes end organ dysfunction and amplified heterotopic ossification formation
Spreadborough P, Strong A, Mares J, Levi B, Davis T
J Orthop Surg Res . 2022 Sep; 17(1):422. PMID: 36123728
Background: Traumatic heterotopic ossification (tHO) is characterized by ectopic bone formation in extra-skeletal sites leading to impaired wound healing, entrapment of neurovascular structures, pain, and reduced range of motion. HO...
10.
Controlling axonal regeneration with acellular nerve allograft limits neuroma formation in peripheral nerve transection: An experimental study in a swine model
Grimm P, Wheatley B, Tomasino A, Leonhardt C, Hunter D, Wood M, et al.
Microsurgery . 2022 Aug; 42(6):603-610. PMID: 35925036
Background: Symptomatic neuromata are a common indication for revision surgery following amputation. Previously described treatments, including traction neurectomy, nerve transposition, targeted muscle re-innervation, and nerve capping, have provided inconsistent results...