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Shailesh Agarwal

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Articles 106
Citations 1716
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Recent Articles
1.
Williams M, Oliphant M, Au V, Liu C, Baril C, OFlanagan C, et al.
Nat Genet . 2024 Nov; 56(12):2753-2762. PMID: 39567747
The prevalence and nature of somatic copy number alterations (CNAs) in breast epithelium and their role in tumor initiation and evolution remain poorly understood. Using single-cell DNA sequencing (49,238 cells)...
2.
Williams M, Oliphant M, Au V, Liu C, Baril C, OFlanagan C, et al.
bioRxiv . 2024 May; PMID: 38746396
Cancer-associated mutations have been documented in normal tissues, but the prevalence and nature of somatic copy number alterations and their role in tumor initiation and evolution is not well understood....
3.
Kratchmarov R, Djeddi S, Dunlap G, He W, Jia X, Burk C, et al.
Nat Immunol . 2024 Apr; 25(5):902-915. PMID: 38589618
Repetitive exposure to antigen in chronic infection and cancer drives T cell exhaustion, limiting adaptive immunity. In contrast, aberrant, sustained T cell responses can persist over decades in human allergic...
4.
Paranzino A, Vieira B, Apovian C, Agarwal S
Plast Reconstr Surg . 2024 Apr; 155(1):207-216. PMID: 38563562
Obesity is one of the greatest public health concerns in the United States and has reached an epidemic scope over the past few decades. Plastic surgery in patients with obesity...
5.
Agarwal S, Gillis L, Wilkie M
Clin J Am Soc Nephrol . 2024 Jan; 20(1):139-146. PMID: 38190135
People treated with peritoneal dialysis (PD) often have complicating conditions that require careful management. Three such conditions are reviewed in this article-diabetes mellitus, polycystic kidney disease, and chronic liver disease....
6.
Chen Z, Ghavimi S, Wu M, McNamara J, Barreiro O, Maridas D, et al.
JCI Insight . 2023 Dec; 8(24). PMID: 38131378
Secondary lymphedema occurs in up to 20% of patients after lymphadenectomy performed for the surgical management of tumors involving the breast, prostate, uterus, and skin. Patients develop progressive edema of...
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Endo Y, Hwang C, Zhang Y, Olumi S, Koh D, Zhu C, et al.
Adv Biol (Weinh) . 2023 Mar; 7(10):e2200320. PMID: 36988414
Aging is associated with loss of skeletal muscle regeneration. Differentially regulated vascular endothelial growth factor (VEGF)A with aging may partially underlies this loss of regenerative capacity. To assess the role...
9.
Endo Y, Samandari M, Karvar M, Mostafavi A, Quint J, Rinoldi C, et al.
Biomaterials . 2023 Feb; 296:122058. PMID: 36841214
Volumetric muscle loss (VML), which refers to a composite skeletal muscle defect, most commonly heals by scarring and minimal muscle regeneration but substantial fibrosis. Current surgical interventions and physical therapy...
10.
Hamnvik O, Agarwal S, AhnAllen C, Goldman A, Reisner S
Transgend Health . 2023 Jan; 7(2):113-116. PMID: 36644516
Due to concerns about the risk of infectious exposures during the coronavirus disease 2019 (COVID-19) pandemic, the uptake of telemedicine has increased rapidly, aided by increased acceptance by clinicians and...