Thomas A Darde
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Explore the profile of Thomas A Darde including associated specialties, affiliations and a list of published articles.
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8
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79
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Recent Articles
1.
Kugathas I, Johansson H, Chan Sock Peng E, Toupin M, Evrard B, Darde T, et al.
Arch Toxicol
. 2023 Jan;
97(3):849-863.
PMID: 36653537
Exposure to endocrine-disrupting chemicals (EDCs) during development may cause reproductive disorders in women. Although female reproductive endpoints are assessed in rodent toxicity studies, a concern is that typical endpoints are...
2.
Davidsen N, Ramhoj L, Lykkebo C, Kugathas I, Poulsen R, Rosenmai A, et al.
Environ Pollut
. 2022 Dec;
317:120709.
PMID: 36462679
No abstract available.
3.
PFOS disrupts key developmental pathways during hiPSC-derived cardiomyocyte differentiation in vitro
Davidsen N, Ramhoj L, Kugathas I, Evrard B, Darde T, Chalmel F, et al.
Toxicol In Vitro
. 2022 Sep;
85:105475.
PMID: 36116746
Exposure to perfluorooctanesulfonic acid (PFOS) has been associated with congenital heart disease (CHD) and decreased birth weight. PFOS exposure can disrupt signaling pathways relevant for cardiac development in stem cell-derived...
4.
Davidsen N, Ramhoj L, Lykkebo C, Kugathas I, Poulsen R, Rosenmai A, et al.
Environ Pollut
. 2022 Apr;
305:119340.
PMID: 35460815
Perfluorooctanesulfonic acid (PFOS) is a persistent anthropogenic chemical that can affect the thyroid hormone system in humans and animals. In adults, thyroid hormones (THs) are regulated by the hypothalamic-pituitary-thyroid (HPT)...
5.
Darde T, Lecluze E, Lardenois A, Stevant I, Alary N, Tuttelmann F, et al.
Bioinformatics
. 2019 Jan;
35(17):3133-3139.
PMID: 30668675
Motivation: Recent advances in transcriptomics have enabled unprecedented insight into gene expression analysis at a single-cell resolution. While it is anticipated that the number of publications based on such technologies...
6.
Darde T, Gaudriault P, Beranger R, Lancien C, Caillarec-Joly A, Sallou O, et al.
Bioinformatics
. 2018 Feb;
34(12):2116-2122.
PMID: 29385404
Motivation: At the same time that toxicologists express increasing concern about reproducibility in this field, the development of dedicated databases has already smoothed the path toward improving the storage and...
7.
Sallou O, Duek P, Darde T, Collin O, Lane L, Chalmel F
Database (Oxford)
. 2016 May;
2016.
PMID: 27173522
Among the 20 000 human gene products predicted from genome annotation, about 3000 still lack validation at protein level. We developed PepPSy, a user-friendly gene expression-based prioritization system, to help...
8.
Darde T, Sallou O, Becker E, Evrard B, Monjeaud C, Le Bras Y, et al.
Nucleic Acids Res
. 2015 Apr;
43(W1):W109-16.
PMID: 25883147
We report the development of the ReproGenomics Viewer (RGV), a multi- and cross-species working environment for the visualization, mining and comparison of published omics data sets for the reproductive science...