Thierry Blachere
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Explore the profile of Thierry Blachere including associated specialties, affiliations and a list of published articles.
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10
Citations
120
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Recent Articles
1.
Wianny F, Blachere T, Godet M, Guillermas R, Cortay V, Bourillot P, et al.
Stem Cell Res
. 2016 Mar;
16(3):557-67.
PMID: 26999759
The imprinted genes of primate embryonic stem cells (ESCs) often show altered DNA methylation. It is unknown whether these alterations emerge while deriving the ESCs. Here we studied the methylation...
2.
Lefevre A, Blachere T
Methods Mol Biol
. 2014 Oct;
1222:209-26.
PMID: 25287349
To question the possible implication of an alteration of the DNA methylation of imprinted genes in normal development failure observed following fertilization in ART centers, it has been necessary to...
3.
Osteil P, Tapponnier Y, Markossian S, Godet M, Schmaltz-Panneau B, Jouneau L, et al.
Biol Open
. 2013 Jun;
2(6):613-28.
PMID: 23789112
Not much is known about the molecular and functional features of pluripotent stem cells (PSCs) in rabbits. To address this, we derived and characterized 2 types of rabbit PSCs from...
4.
Sauvat F, Bouilly J, Capito C, Lefevre A, Blachere T, Borenstein N, et al.
FASEB J
. 2012 Dec;
27(4):1511-8.
PMID: 23271057
As a result of advances in medical treatment, almost 80% of children who are diagnosed with cancer survive long-term. The adverse consequences of cancer treatments include impaired puberty and fertility....
5.
Khoueiry R, Ibala-Romdhane S, Al-Khtib M, Blachere T, Lornage J, Guerin J, et al.
Zygote
. 2012 Feb;
21(2):129-38.
PMID: 22300968
Summary To evaluate the integrity of genomic imprinting in embryos that failed to develop normally following intracytoplasmic sperm injection (ICSI), we analysed the methylation profile of H19 and KCNQ1OT1 imprinting...
6.
Ibala-Romdhane S, Al-Khtib M, Khoueiry R, Blachere T, Guerin J, Lefevre A
Eur J Hum Genet
. 2011 Jun;
19(11):1138-43.
PMID: 21654730
ART is suspected to generate increased imprinting errors in the lineage. Following an intra cytoplasmic sperm injection (ICSI) procedure, a certain number of embryos fail to develop normally and imprinting...
7.
Al-Khtib M, Perret A, Khoueiry R, Ibala-Romdhane S, Blachere T, Greze C, et al.
Fertil Steril
. 2011 Mar;
95(6):1955-60.
PMID: 21420679
Objective: To evaluate the integrity of genomic imprinting in oocytes vitrified at the germinal vesicle (GV) stage and in vitro matured (IVM) after thawing. Design: Clinical research and application. Setting:...
8.
Borghol N, Blachere T, Lefevre A
Genomics
. 2008 Mar;
91(5):415-22.
PMID: 18343090
The use of round spermatids that are fully active at the transcriptional level to create zygotes (i.e. round spermatid injection; ROSI) raises the question regarding the downregulation of all specific...
9.
Borghol N, Lornage J, Blachere T, Sophie Garret A, Lefevre A
Genomics
. 2005 Dec;
87(3):417-26.
PMID: 16378710
Imprinting is an epigenetic modification that is reprogrammed in the germ line and leads to the monoallelic expression of some genes. Imprinting involves DNA methylation. Maternal imprint is reset during...
10.
Coulon S, Pellequer J, Blachere T, Chartier M, Mappus E, Cuilleron C, et al.
J Mol Recognit
. 2002 Mar;
15(1):6-18.
PMID: 11870917
The high-affinity monoclonal anti-estradiol antibody 9D3 presents a specificity defect towards estradiol-3-sulphate and 3-glucuronide conjugates incompatible with use in direct immunoassays. The corresponding single-chain variable fragment (scFv), cloned and produced...